Evidence map›Paper›PMID 40725371›Full record

ReviewInsects2025

The Role of Heat Shock Proteins in Insect Stress Response, Immunity, and Climate Adaptation.

Davide Banfi, Tommaso Bianchi, Maristella Mastore, Maurizio Francesco Brivio

Abstract readReview
In one paragraph

Review in Insects, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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  13. Stage-Specific Proteomic Adaptations to Heme-Induced Oxidative Stress inInternational journal of molecular sciences · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Davide BanfiLaboratory of Applied Entomology and Parasitology, Department of Theoretical and Applied Sciences (DiSTA), University of Insubria, 21100 Varese, Italy.ORCID 0009-0002-0791-5919
Tommaso BianchiLaboratory of Applied Entomology and Parasitology, Department of Theoretical and Applied Sciences (DiSTA), University of Insubria, 21100 Varese, Italy.ORCID 0009-0006-4826-9385
Maristella MastoreLaboratory of Applied Entomology and Parasitology, Department of Theoretical and Applied Sciences (DiSTA), University of Insubria, 21100 Varese, Italy.ORCID 0000-0003-0514-521X
Maurizio Francesco BrivioLaboratory of Applied Entomology and Parasitology, Department of Theoretical and Applied Sciences (DiSTA), University of Insubria, 21100 Varese, Italy.ORCID 0000-0002-1002-0422

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heat shock proteins (HSPs) play a key role in enhancing insect resilience to abiotic and biotic stresses by preserving cellular integrity and modulating immune responses. This review summarizes the main functions of HSPs in insects, including protein stabilization, interaction with antioxidant systems, and involvement in the innate immune response. The expression of HSPs under environmental conditions reflects their evolutionary adaptation to various stressors, including thermal changes, chemical exposure, and pathogens. Future research should focus on the interaction between HSPs and other stress response systems to improve our understanding of insect adaptation. Furthermore, in the context of global climate change, HSPs emerge as a crucial resilience factor and potential biomarkers for environmental monitoring.

Indexed as

abiotic stressbiotic stressclimate changeHSPimmunityinsects

Identifiers

PMID40725371
PMCPMC12295638

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.