Evidence map›Paper›PMID 40725261›Full record

ArticleInternational journal of molecular sciences2025

Correlation and Risk Assessment of Inflammation-Based Parameters on Cardiovascular Parameters and Clinical Events in Giant Cell Arteritis: A Retrospective Study.

Leyla Schweiger, Andreas Meinitzer, Dieter Szolar, Marianne Brodmann, Christian Dejaco, Franz Hafner, Philipp Jud

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Leyla SchweigerDivision of Angiology, Department of Internal Medicine, Medical University of Graz, 8036 Graz, Austria.
Andreas MeinitzerInstitute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0002-7883-7973
Dieter SzolarDiagnostikum Graz Süd-West, 8054 Graz, Austria.
Marianne BrodmannDivision of Angiology, Department of Internal Medicine, Medical University of Graz, 8036 Graz, Austria.
Christian DejacoDivision of Rheumatology, Department of Internal Medicine, Medical University of Graz, 8036 Graz, Austria.
Franz HafnerDivision of Angiology, Department of Internal Medicine, Medical University of Graz, 8036 Graz, Austria.
Philipp JudDivision of Angiology, Department of Internal Medicine, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0002-0832-1322

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated associations of inflammation-based biomarkers with endothelial dysfunction and lipids and their predictive value for clinical outcome parameters in patients with giant cell arteritis (GCA). A total of 138 patients with inactive GCA were retrospectively analyzed to investigate potential differences in inflammatory biomarkers regarding clinical GCA subtypes and potential correlations between inflammatory parameters with markers of endothelial dysfunction and lipid parameters. Additionally, the predictive role of inflammatory biomarkers for clinical outcomes, including disease relapse, all-cause mortality, cardiovascular events, and glucocorticoid adverse effects, was analyzed. GCA individuals without concomitant symptoms of polymyalgia rheumatica and those who received initial glucocorticoid pulse therapy exhibited significantly higher levels of white blood cells and neutrophils (all with

Indexed as

Cardiovascular DiseasesGiant Cell ArteritisInflammationAgedAged, 80 and overBiomarkersFemaleGlucocorticoidsHumansMaleMiddle AgedNeutrophilsRetrospective StudiesRisk AssessmentBiomarkersGlucocorticoidsbiomarkerscardiovascular riskgiant cell arteritisinflammation

Identifiers

PMID40725261
PMCPMC12295461

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.