Evidence map›Paper›PMID 40725257›Full record

ArticleInternational journal of molecular sciences2025

Multivalent Immune-Protective Effects of Egg Yolk Immunoglobulin Y (IgY) Derived from Live or Inactivated

Jing Chen, Pan Cui, Huihui Xiao, Xiaohui Han, Ziye Ma, Xiaoqing Wu, Juan Lu, Guoping Zhu, Yong Liu, Xiang Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. SXP01: a novel bacteriophage for combatingFrontiers in microbiology · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jing ChenAnhui Province Key Laboratory of Embryo Development and Reproductive Regulation, Fuyang Normal University, Fuyang 236041, China.
Pan CuiAnhui Province Key Laboratory of Embryo Development and Reproductive Regulation, Fuyang Normal University, Fuyang 236041, China.
Huihui XiaoAnhui Province Key Laboratory of Embryo Development and Reproductive Regulation, Fuyang Normal University, Fuyang 236041, China.
Xiaohui HanAnhui Province Key Laboratory of Embryo Development and Reproductive Regulation, Fuyang Normal University, Fuyang 236041, China.
Ziye MaAnhui Province Key Laboratory of Embryo Development and Reproductive Regulation, Fuyang Normal University, Fuyang 236041, China.
Xiaoqing WuAnhui Province Key Laboratory of Embryo Development and Reproductive Regulation, Fuyang Normal University, Fuyang 236041, China.
Juan LuRural Revitalization Collaborative Technology Service Center of Anhui Province, Fuyang Normal University, Fuyang 236041, China.
Guoping ZhuAnhui Provincial Key Laboratory of Molecular Enzymology and Mechanism of Major Metabolic Diseases, Auhui Provincial Engineering Research Centre for Molecular Detection and Diagnostics, College of Life Sciences, Anhui Normal University, Wuhu 241000, China.
Yong LiuAnhui Province Key Laboratory of Embryo Development and Reproductive Regulation, Fuyang Normal University, Fuyang 236041, China.
Xiang LiuAnhui Province Key Laboratory of Embryo Development and Reproductive Regulation, Fuyang Normal University, Fuyang 236041, China.

Funding

the Biological and Medical Sciences of Applied Summit Nurturing Disciplines in Anhui Province Anhui Education Secretary Department [2023]13the College Student Innovation and Entrepreneurship Project of Anhui Province S202210371092 and S202310371056the Key Projects of Scientific Research Plan of Colleges and Universities of Anhui Province 2022AH051330the Outstanding Innovative Research Team for Molecular Enzymology and Detection in Anhui Provincial Universities 2022AH010012the University Collaborative Innovation Project of Anhui Province GXXT-2023-077the University Synergy Innovation Program of Anhui Province GXXT-2022-067
6 · The paper itself

Abstract

Egg yolk immunoglobulin Y (IgY) possesses advantages such as low cost, easy availability, simple preparation, high antigen specificity, absence of drug residues, and compliance with animal welfare standards, making it an environmentally friendly and safe alternative to antibiotics. This research utilizes IgY antibody technology to develop a multivalent passive immune vaccine for major pathogenic bacteria in aquaculture. In this study, IgY antibodies against live

Indexed as

Egg YolkFish DiseasesGram-Negative Bacterial InfectionsImmunoglobulinsShewanellaAeromonas hydrophilaAnimalsAntibodies, BacterialAquacultureChickensFemaleGoldfishImmunization, PassiveAntibodies, BacterialIgYImmunoglobulinsAeromonas hydrophilaIgY antibodymultivalent vaccinepassive immunityShewanella xiamenensis

Identifiers

PMID40725257
PMCPMC12295794

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.