Evidence map›Paper›PMID 40725252›Full record

ReviewInternational journal of molecular sciences2025

Review of Recent Medicinal Applications of Rhenium(I) Tricarbonyl Complexes.

Erick Kipngetich Towett, Vuyelwa J Tembu, Douglas Kemboi, Moses K Langat, Amanda-Lee E Manicum

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erick Kipngetich TowettDepartment of Chemistry, Tshwane University of Technology, P.O. Box X680, Pretoria 0001, South Africa.ORCID 0000-0002-8135-9490
Vuyelwa J TembuDepartment of Chemistry, Tshwane University of Technology, P.O. Box X680, Pretoria 0001, South Africa.
Douglas KemboiDepartment of Physical and Biological Sciences, University of Kabianga, Kericho P.O. Box 2030, Kenya.ORCID 0000-0003-3771-128X
Moses K LangatRoyal Botanic Gardens Kew, Richmond, Surrey TW9 3AE, UK.ORCID 0000-0001-8079-7774
Amanda-Lee E ManicumDepartment of Chemistry, Tshwane University of Technology, P.O. Box X680, Pretoria 0001, South Africa.ORCID 0000-0003-4064-1307

Funding

NRF South Africa 129468NRF South Africa PMDS23041793997
6 · The paper itself

Abstract

The use of metal-based complexes is currently taking centre stage in the field of nanomedicine for the treatment and control of various ailments. Rhenium(I) tricarbonyl complexes have frequently been evaluated in vitro for their anticancer activities, and a few have advanced to in vivo and clinical trials, owing to the distinct application characteristics of these complexes. Their inception in drug development is key. This study explores a detailed chronological overview of the medical applications of Re(I) tricarbonyl complexes over the past six years (2019-2024), focusing on their applications and clinical tests in the control and management of various ailments. An in-depth examination of their activities in anticancer treatments, Chagas disease, antifungal infections, antimalarial, and microbial infections was conducted, comparing the complexes to various standard antibiotics, conventional antimalarial drugs, antifungals, and standard anticancer agents.

Indexed as

Coordination ComplexesRheniumAnimalsAnti-Infective AgentsAntimalarialsAntineoplastic AgentsHumansAnti-Infective AgentsAntimalarialsAntineoplastic AgentsCoordination ComplexesRheniumantichagasicantimalarialantimicrobialdiagnosticsRe(I) tricarbonyltherapeutics

Identifiers

PMID40725252
PMCPMC12294928

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.