Evidence map›Paper›PMID 40725240›Full record

ArticleInternational journal of molecular sciences2025

Human Dialyzable Leukocyte Extract Enhances Albendazole Efficacy and Promotes Th1/Th2-Biased Lymphocyte and Antibody Responses in Peritoneal Cavity of Murine Model of

Gabriela Hrčková, Dagmar Mudroňová, Katarína Reiterová, Serena Cavallero, Ilaria Bellini

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gabriela HrčkováInstitute of Parasitology of the Slovak Academy of Sciences, 04001 Košice, Slovakia.ORCID 0000-0002-6994-8751
Dagmar MudroňováDepartment of Microbiology and Immunology, University of Veterinary Medicine and Pharmacy, 04001 Košice, Slovakia.ORCID 0000-0002-8007-6237
Katarína ReiterováInstitute of Parasitology of the Slovak Academy of Sciences, 04001 Košice, Slovakia.
Serena CavalleroDepartment of Public Health and Infectious Diseases, Sapienza, University of Rome, 00185 Rome, Italy.ORCID 0000-0002-2245-9694
Ilaria BelliniDepartment of Public Health and Infectious Diseases, Sapienza, University of Rome, 00185 Rome, Italy.ORCID 0009-0002-2218-7550

Funding

the Scientific Grant Agency of the Ministry of Education of the Slovak Republic and the Slovak Academy of Sciences, APVV - 17-0410
6 · The paper itself

Abstract

Human leukocyte extract (HLE), a non-immunogenic dialyzable leukocyte preparation (<10 kDa), may serve as a safe adjuvant in immunotherapy. We investigated the effects of albendazole (ABZ), HLE, and their combination in

Indexed as

AlbendazoleAntibody FormationLeukocytesTh1 CellsTh2 CellsAnimalsCytokinesDisease Models, AnimalFemaleHumansMiceMice, Inbred BALB CPeritoneal CavityAlbendazoleCytokinesalbendazoleantibodieshuman dialyzable leukocyte extractimmunotherapylymphocytesmiceparasite Mesocestoides vogaeperitoneal cavity

Identifiers

PMID40725240
PMCPMC12295987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.