Evidence map›Paper›PMID 40725222›Full record

ReviewInternational journal of molecular sciences2025

Mechanistic Insight into the Antioxidant and Antimicrobial Activities of Palm Oil-Derived Biomaterials: Implications for Dental and Therapeutic Applications.

Syafira Masri, Nurulhuda Mohd, Noor Hayaty Abu Kasim, Masfueh Razali

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Syafira MasriDepartment of Restorative Dentistry, Faculty of Dentistry, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur 50300, Malaysia.
Nurulhuda MohdDepartment of Restorative Dentistry, Faculty of Dentistry, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur 50300, Malaysia.ORCID 0000-0002-4021-1668
Noor Hayaty Abu KasimDepartment of Restorative Dentistry, Faculty of Dentistry, Universiti Malaya, Kuala Lumpur 50603, Malaysia.
Masfueh RazaliDepartment of Restorative Dentistry, Faculty of Dentistry, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur 50300, Malaysia.ORCID 0000-0001-6679-9319

Funding

Collaborative Research in Engineering, Science and Technology Centre CREST-2024-002
6 · The paper itself

Abstract

Palm oil is a highly versatile natural resource that has gathered significant attention due to its bioactive properties, particularly its antimicrobial and antioxidant effects. Rich in tocotrienols, tocopherols, and carotenoids, palm oil exhibits potent antioxidant activity, while its fatty acid content and other bioactive molecules contribute to its antimicrobial efficacy against various pathogens. The underlying mechanisms of action driving these bioactivities involve intricate molecular interactions, biochemical pathways, and redox processes, which influence microbial cell function and oxidative stress reduction. This review provides a critical analysis of the current mechanistic understanding of palm oil's biofunctional properties, emphasizing its potential incorporation into engineered biomaterials. Particular focus is given to the chemical composition, reaction pathways, and synergistic potential of palm oil derivatives in material-based formulations. Furthermore, the potential applications of palm oil as a standalone or synergistic agent in novel therapeutic and industrial formulations are explored. By elucidating the mechanistic basis of its bioactivity within material contexts, this review highlights palm oil's promising role in the development of advanced functional materials for pharmaceutical and dental technologies.

Indexed as

Anti-Infective AgentsAntioxidantsBiocompatible MaterialsPalm OilAnimalsHumansAnti-Infective AgentsAntioxidantsBiocompatible MaterialsPalm Oilantimicrobial activityantioxidant propertiespalm oil compoundsthree-dimensional bioprintingtissue engineering

Identifiers

PMID40725222
PMCPMC12296099

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.