Evidence map›Paper›PMID 40725171›Full record

ArticleInternational journal of molecular sciences2025

Design, Synthesis, and Testing of 1,2,3-Triazolo-Quinobenzothiazine Hybrids for Cytotoxic and Immunomodulatory Activity.

Klaudia Giercuszkiewicz-Haśnik, Magdalena Skonieczna, Beata Morak-Młodawska, Małgorzata Jeleń

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Klaudia Giercuszkiewicz-HaśnikDepartment of Systems Biology and Engineering, The Silesian University of Technology, Akademicka Street 16, 44-100 Gliwice, Poland.ORCID 0009-0008-9665-1065
Magdalena SkoniecznaDepartment of Systems Biology and Engineering, The Silesian University of Technology, Akademicka Street 16, 44-100 Gliwice, Poland.ORCID 0000-0002-6263-9585
Beata Morak-MłodawskaDepartment of Organic Chemistry, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Jagiellońska Street 4, 41-200 Sosnowiec, Poland.ORCID 0000-0001-5389-1079
Małgorzata JeleńDepartment of Organic Chemistry, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Jagiellońska Street 4, 41-200 Sosnowiec, Poland.ORCID 0000-0002-4144-990X

Funding

Medical University of Silesia in Katowice BNW-1-100/K/4/FSilesian University of Technology 02/040/BK25/1070
6 · The paper itself

Abstract

Phenothiazines, mainly known for their antipsychotic activity, have recently attracted attention as potential compounds with anticancer and immunomodulatory activity In this study, 20 new quinobenzothiazines (

Indexed as

Antineoplastic AgentsBenzothiazolesTriazolesApoptosisCell Line, TumorCell SurvivalDrug DesignHumansAntineoplastic AgentsBenzothiazolesTriazolesAIFM2apoptosisBCL2BEAS-2BIL6IL8inflammatory responseMDM2quinobenzothiazineRT-qPCR analysis

Identifiers

PMID40725171
PMCPMC12295927

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.