Evidence map›Paper›PMID 40725149›Full record

ArticleInternational journal of molecular sciences2025

Identification and Screening of Novel Antimicrobial Peptides from Medicinal Leech via Heterologous Expression in

Maria Serebrennikova, Ekaterina Grafskaia, Daria Kharlampieva, Ksenia Brovina, Pavel Bobrovsky, Sabina Alieva, Valentin Manuvera, Vassili Lazarev

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maria SerebrennikovaMoscow Center for Advanced Studies 20, Kulakova Str., Moscow 123592, Russia.ORCID 0009-0002-1663-9311
Ekaterina GrafskaiaLaboratory of Genetic Engineering, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow 119435, Russia.ORCID 0000-0001-8957-6142
Daria KharlampievaLaboratory of Genetic Engineering, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow 119435, Russia.ORCID 0000-0002-3514-2303
Ksenia BrovinaMoscow Center for Advanced Studies 20, Kulakova Str., Moscow 123592, Russia.ORCID 0009-0001-6309-2817
Pavel BobrovskyMoscow Center for Advanced Studies 20, Kulakova Str., Moscow 123592, Russia.ORCID 0000-0001-5735-0042
Sabina AlievaLaboratory of Genetic Engineering, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow 119435, Russia.
Valentin ManuveraMoscow Center for Advanced Studies 20, Kulakova Str., Moscow 123592, Russia.ORCID 0000-0002-2471-0563
Vassili LazarevMoscow Center for Advanced Studies 20, Kulakova Str., Moscow 123592, Russia.

Funding

Russian Science Foundation No. 23-15-00084
6 · The paper itself

Abstract

The growing threat of infectious diseases requires novel therapeutics with different mechanisms of action. Antimicrobial peptides (AMPs), which are crucial for innate immunity, are a promising research area. The medicinal leech (

Indexed as

Antimicrobial Cationic PeptidesAntimicrobial PeptidesEscherichia coliHirudo medicinalisAmino Acid SequenceAnimalsAnti-Bacterial AgentsBacillus subtilisGene ExpressionMicrobial Sensitivity TestsRecombinant ProteinsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesAntimicrobial PeptidesRecombinant Proteinsantibacterial activityantimicrobial peptidesEscherichia coligene expressiongenetic engineeringHirudo medicinalismedicinal leech

Identifiers

PMID40725149
PMCPMC12295236

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.