Evidence map›Paper›PMID 40725094›Full record

ArticleInternational journal of molecular sciences2025

TrkA Expression as a Novel Prognostic Biomarker in Oral Squamous Cell Carcinoma.

Aleksandra Ciarka, Filip Skowronek, Przemysław Miłosz, Michał Kunc, Robert Burdach, Monika Sakowicz-Burkiewicz, Barbara Jereczek-Fossa, Anna Starzyńska, Rafał Pęksa

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Aleksandra CiarkaDepartment of Pathomorphology, Medical University of Gdansk, 7 Dębinki Street, 80-211 Gdańsk, Poland.ORCID 0000-0002-6799-5829
Filip SkowronekStudent Scientific Circle, Department of Cardiac Surgery, Medical University of Silesia, 15 Poniatowski Street, 40-055 Katowice, Poland.
Przemysław MiłoszStudent Scientific Circle, Department of Pathomorphology, Medical University of Gdansk, 7 Dębinki Street, 80-211 Gdańsk, Poland.
Michał KuncDepartment of Pathomorphology, Medical University of Gdansk, 7 Dębinki Street, 80-211 Gdańsk, Poland.ORCID 0000-0001-9529-2381
Robert BurdachDepartment of Oral Surgery, Medical University of Gdansk, 7 Dębinki Street, 80-211 Gdansk, Poland.
Monika Sakowicz-BurkiewiczDepartment of Molecular Medicine, Medical University of Gdansk, 7 Dębinki Street, 80-211 Gdansk, Poland.
Barbara Jereczek-FossaDepartment of Oncology and Hemato-Oncology, University of Milan, 7 Festa del Perdono Street, 20-112 Milan, Italy.
Anna StarzyńskaDepartment of Oral Surgery, Medical University of Gdansk, 7 Dębinki Street, 80-211 Gdansk, Poland.ORCID 0000-0001-6900-0429
Rafał PęksaDepartment of Pathomorphology, Medical University of Gdansk, 7 Dębinki Street, 80-211 Gdańsk, Poland.ORCID 0000-0002-4904-7059

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC) remains a significant global health challenge, representing 90% of oral malignancies. Despite therapeutic advances, patient outcomes remain poor, highlighting the need for novel prognostic biomarkers and treatment targets. We investigated the expression patterns of

Indexed as

Biomarkers, TumorCarcinoma, Squamous CellMouth NeoplasmsReceptor, trkAAdultAgedAged, 80 and overFemaleGene Expression Regulation, NeoplasticHumansKaplan-Meier EstimateMaleMembrane GlycoproteinsMiddle AgedPrognosisReceptor, trkBBiomarkers, TumorMembrane GlycoproteinsNTRK1 protein, humanReceptor, trkAReceptor, trkBReceptor, trkCtropomyosin-related kinase-B, humanbiomarkerNTRKoral squamous cell carcinomaprognosisTrkA

Identifiers

PMID40725094
PMCPMC12295489

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.