Evidence map›Paper›PMID 40725000›Full record

ArticleInternational journal of molecular sciences2025

In Silico Evaluation of Quinolone-Triazole and Conazole-Triazole Hybrids as Promising Antimicrobial and Anticancer Agents.

Humaera Noor Suha, Mansour H Almatarneh, Raymond A Poirier, Kabir M Uddin

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Humaera Noor SuhaDepartment of Biochemistry and Microbiology, North South University, Dhaka 1229, Bangladesh.
Mansour H AlmatarnehDepartment of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia.
Raymond A PoirierDepartment of Chemistry, Memorial University, St. John's, NL A1B 3X7, Canada.
Kabir M UddinDepartment of Biochemistry and Microbiology, North South University, Dhaka 1229, Bangladesh.ORCID 0000-0002-5518-2345

Funding

Deanship of Scientific Research at Imam Mohammad Ibn Saud Islamic University (IMSIU) IMSIU-DDRSP2501
6 · The paper itself

Abstract

Cancer remains one of the leading causes of death globally, highlighting the urgent need for novel anticancer therapies with higher efficacy and reduced toxicity. Similarly, the rise in multidrug-resistant pathogens and emerging infectious diseases underscores the critical demand for new antimicrobial agents that target resistant infections through unique mechanisms. This study used computational approaches to investigate twenty quinolone-triazole and conazole-triazole hybrid derivatives as antimicrobial and anticancer agents (

Indexed as

Anti-Infective AgentsAntineoplastic AgentsQuinolonesTriazolesComputer SimulationDNA GyraseHumansMicrobial Sensitivity TestsMolecular Docking SimulationMolecular Dynamics SimulationAnti-Infective AgentsAntineoplastic AgentsDNA GyraseQuinolonesTriazolesanticancerantimicrobialconazolequinolonetriazole

Identifiers

PMID40725000
PMCPMC12294901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.