Evidence map›Paper›PMID 40724960›Full record

ArticleInternational journal of molecular sciences2025

Citrate Transporter Expression and Localization: The

Jan C-C Hu, Tian Liang, Hong Zhang, Yuanyuan Hu, Yasuo Yamakoshi, Ryuji Yamamoto, Chuhua Zhang, Hui Li, Charles E Smith, James P Simmer

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Citrate Transporter NaCT and Enamel Mineralization: TheInternational journal of molecular sciences · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jan C-C HuDepartment of Biologic and Materials Sciences & Prosthodontics, University of Michigan School of Dentistry, 1011 N University Ave., Ann Arbor, MI 48109, USA.ORCID 0000-0002-9294-0248
Tian LiangDepartment of Orthodontic and Pediatric Dentistry, University of Michigan School of Dentistry, 1011 N University Ave., Ann Arbor, MI 48109, USA.ORCID 0000-0002-3429-7821
Hong ZhangDepartment of Biologic and Materials Sciences & Prosthodontics, University of Michigan School of Dentistry, 1011 N University Ave., Ann Arbor, MI 48109, USA.ORCID 0000-0003-4558-9026
Yuanyuan HuDepartment of Orthodontic and Pediatric Dentistry, University of Michigan School of Dentistry, 1011 N University Ave., Ann Arbor, MI 48109, USA.ORCID 0009-0000-6852-8790
Yasuo YamakoshiDepartment of Biochemistry and Molecular Biology, School of Dental Medicine, Tsurumi University, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama 230-8501, Japan.ORCID 0000-0003-2134-5860
Ryuji YamamotoDepartment of Biochemistry and Molecular Biology, School of Dental Medicine, Tsurumi University, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama 230-8501, Japan.
Chuhua ZhangDepartment of Biologic and Materials Sciences & Prosthodontics, University of Michigan School of Dentistry, 1011 N University Ave., Ann Arbor, MI 48109, USA.
Hui LiDepartment of Biologic and Materials Sciences & Prosthodontics, University of Michigan School of Dentistry, 1011 N University Ave., Ann Arbor, MI 48109, USA.
Charles E SmithDepartment of Biologic and Materials Sciences & Prosthodontics, University of Michigan School of Dentistry, 1011 N University Ave., Ann Arbor, MI 48109, USA.
James P SimmerDepartment of Biologic and Materials Sciences & Prosthodontics, University of Michigan School of Dentistry, 1011 N University Ave., Ann Arbor, MI 48109, USA.ORCID 0000-0002-7192-6105

Funding

DSPP Function, Pathophysiology, and Genetic DiagnosisR01DE027675 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SIMMER, JAMES P · 2018 to 2022
$2.4M
Development and Validation of Novel Amelogenesis ModelsUH3DE028849 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HU, JAN CHING CHUN · 2021 to 2022
$621k
Development and Validation of Novel Amelogenesis ModelsUG3DE028849 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HU, JAN CHING CHUN · 2019 to 2020
$619k
Genetic Mechanisms of Amelogenesis ImperfectaR56DE015846 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HU, JAN CHING CHUN · 2021 to 2021
$402k
NIDCR NIH HHS R01 DE027675NIDCR NIH HHS R56 DE015846NIDCR NIH HHS UG3 DE028849NIDCR NIH HHS UH3 DE028849NIH HHS 1R01DE027675-05NIH HHS 1R01DE028849-05
6 · The paper itself

Abstract

The sodium-citrate cotransporter (NaCT) plays a crucial role in citrate transport during amelogenesis. Mutations in the

Indexed as

Citric AcidSymportersAmeloblastsAnimalsDental EnamelDicarboxylic Acid TransportersDisease Models, AnimalMiceMice, Inbred C57BLMice, TransgenicCitric AcidDicarboxylic Acid TransportersSlc13a5 protein, mouseSymportersamelogenesisenamel mineralizationprotein localization

Identifiers

PMID40724960
PMCPMC12294767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.