Evidence map›Paper›PMID 40724832›Full record

ArticleInternational journal of molecular sciences2025

Dirhodium Tetraacetate Binding to Lysozyme at Body Temperature.

Gabriella Tito, Giarita Ferraro, Antonello Merlino

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Temperature and intrinsic CaNature structural & molecular biology · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gabriella TitoDepartment of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy.
Giarita FerraroDepartment of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy.ORCID 0000-0001-9385-2429
Antonello MerlinoDepartment of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy.ORCID 0000-0002-1045-7720

Funding

MIUR PRIN2022 (project code: 2022JMFC3X, "Protein Metalation by Anticancer Metal-based Drugs") 2022JMFC3X
6 · The paper itself

Abstract

Paddlewheel dirhodium complexes are cytotoxic compounds that are also used as catalysts and in the formation of Rh-based artificial metalloenzymes. Low-temperature structures of adducts formed by the model protein hen egg white lysozyme (HEWL) with dirhodium tetraacetate ([Rh

Indexed as

Body TemperatureMuramidaseRhodiumAnimalsBinding SitesChickensCrystallography, X-RayModels, MolecularProtein BindingTemperaturehen egg lysozymeMuramidaseRhodiumbody temperature crystallographydirhodium compoundsmetal complexesmetallodrugsprotein metalation

Identifiers

PMID40724832
PMCPMC12294737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.