Evidence map›Paper›PMID 40724823›Full record

ArticleInternational journal of molecular sciences2025

In Experimental Tuberculosis Infection, the Bacteriostatic Function of Macrophages Is Activated by Th1 CD4

Vladimir V Evstifeev, Konstantin B Majorov, Vadim G Avdienko, Vladimir V Yeremeev, Galina S Shepelkova

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vladimir V EvstifeevCentral Tuberculosis Research Institute, Moscow 107564, Russia.
Konstantin B MajorovCentral Tuberculosis Research Institute, Moscow 107564, Russia.
Vadim G AvdienkoCentral Tuberculosis Research Institute, Moscow 107564, Russia.
Vladimir V YeremeevCentral Tuberculosis Research Institute, Moscow 107564, Russia.ORCID 0000-0001-6608-7557
Galina S ShepelkovaCentral Tuberculosis Research Institute, Moscow 107564, Russia.ORCID 0000-0001-6854-7932

Funding

Russian Foundation for Basic Research 13-04-01358Russian Scientific Programs FURE-2025-0018
6 · The paper itself

Abstract

The pivotal component in the protection against TB is the tissue macrophages (Mф). These cells have been demonstrated to play a crucial role in the elimination of pathogens and mycobacterial killing. Elucidation of the molecular and phenotypic events that determine the outcome of infection in Mф is fundamental to understanding the key features of these cells that are so important in fighting infection. Mф activation is driven by cytokines and other inflammatory mediators secreted by T lymphocytes. The interaction between

Indexed as

Macrophage ActivationMacrophagesMycobacterium tuberculosisNitritesTh1 CellsTuberculosisAnimalsMiceMice, Inbred C57BLNitritesCD27macrophagenitrite-independent mechanism of activationTh1 effector T celltuberculosis

Identifiers

PMID40724823
PMCPMC12295194

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.