Evidence map›Paper›PMID 40724676›Full record

ReviewHealthcare (Basel, Switzerland)2025

Cold Knife Hysteroscopic Myomectomy: A Literature Review on Its Role as a Fertility Sparing Tool.

Giuseppe Gullo, Valentina Billone, Erika Catania, Giulia Russo, Stamatios Petousis, Lina De Paola, Elena Chitoran, Gaspare Cucinella, Simone Ferrero

Abstract readReview
In one paragraph

Review in Healthcare (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Giuseppe GulloDepartment of Obstetrics and Gynaecology, AOOR Villa Sofia-Cervello, University of Palermo, 90133 Palermo, Italy.ORCID 0000-0003-4269-4269
Valentina BilloneDepartment of Obstetrics and Gynaecology, AOOR Villa Sofia-Cervello, University of Palermo, 90133 Palermo, Italy.
Erika CataniaDepartment of Obstetrics and Gynaecology, AOOR Villa Sofia-Cervello, University of Palermo, 90133 Palermo, Italy.
Giulia RussoDepartment of Obstetrics and Gynaecology, AOOR Villa Sofia-Cervello, University of Palermo, 90133 Palermo, Italy.
Stamatios Petousis2nd Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.ORCID 0000-0002-5564-0406
Lina De PaolaDepartment of Anatomical, Histological, Forensic and Orthopedic Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0009-0001-4631-1061
Elena ChitoranGeneral Surgery and Surgical Oncology Department I, Bucharest Institute of Oncology "Al. Trestioreanu", 022328 Bucharest, Romania.ORCID 0000-0001-9225-8030
Gaspare CucinellaDepartment of Obstetrics and Gynaecology, AOOR Villa Sofia-Cervello, University of Palermo, 90133 Palermo, Italy.
Simone FerreroDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, 16132 Genoa, Italy.ORCID 0000-0003-2225-5568

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cold knife hysteroscopic myomectomy (CKHM) is a minimally invasive surgical technique used to remove submucosal fibroids, commonly associated with infertility.

methodsA comprehensive literature search was conducted across databases including PubMed, Scopus, and Google Scholar, focusing on studies published from 2011 to 2024. The aim of this narrative review was to highlight the minimally invasive cold loop resectoscopic approach for the treatment of submucosal fibroids.

resultsThe review revealed that CKHM is associated with favorable fertility outcomes, with studies reporting increased pregnancy rates; most studies indicated that CKHM did not negatively affect endometrial function.

conclusionsCold knife hysteroscopic myomectomy is a safe and effective option for women with submucosal fibroids who wish to preserve fertility due its minimal invasiveness and low complication rates.

Indexed as

cold knife hysteroscopic myomectomyfertility sparingfibroidsresectoscopy

Identifiers

PMID40724676
PMCPMC12295589

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.