Evidence map›Paper›PMID 40724567›Full record

ArticleLife (Basel, Switzerland)2025

Potential Clinical Use of CytoSorb

Gabriele Melegari, Fabio Gazzotti, Federica Arturi, Elisabetta Bertellini, Andrea Tognù, Domenico Pietro Santonastaso, Matteo Villani, Francesca Coppi, Fabrizio Fattorini, Fabio Catani and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gabriele MelegariDepartment of Anaesthesia and Intensive Care, Azienda Ospedaliero Universitaria, Policlinico di Modena, Via Del pozzo 71, 41121 Modena, Italy.ORCID 0000-0003-4512-4835
Fabio GazzottiDepartment of Anaesthesia and Intensive Care, Azienda Ospedaliero Universitaria, Policlinico di Modena, Via Del pozzo 71, 41121 Modena, Italy.
Federica ArturiSchool of Anaesthesia and Intensive Care, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Elisabetta BertelliniSchool of Medicine, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Andrea TognùDepartment of Anaesthesia and Intensive Care, Gaetano Pini Hospital, 20122 Milano, Italy.ORCID 0000-0002-8840-4872
Domenico Pietro SantonastasoDepartment of Anaesthesia and Intensive Care, Bufalini Hospital, Azienda USL Romagna, 47521 Cesena, Italy.ORCID 0000-0003-1304-7724
Matteo VillaniDepartment of Anaesthesia and Intensive Care, Azienda Ospedaliero Universitaria, Policlinico di Parma, 56126 Pisa, Italy.ORCID 0000-0003-4269-6096
Francesca CoppiDepartment of Cardiology, Azienda Ospedaliero Universitaria, Policlinico di Modena, 41121 Modena, Italy.ORCID 0000-0001-7715-6941
Fabrizio FattoriniDepartment of Anesthesia and Intensive Care, Ospedale San Sebastiano, 00044 Frascati, Italy.
Fabio CataniDepartment of Orthopedic Surgery, University of Modena and Reggio Emilia, Azienda Ospedaliero Universitaria, Policlinico di Modena, 41121 Modena, Italy.
Alberto BarbieriSchool of Anaesthesia and Intensive Care, University of Modena and Reggio Emilia, 41125 Modena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMajor orthopedic trauma in patients receiving anticoagulants such as ticagrelor or rivaroxaban poses a significant perioperative challenge, particularly in emergency contexts where bleeding risks are heightened and specific reversal agents may be unavailable. CytoSorb

objectiveThis protocol describes a prospective clinical investigation assessing the feasibility and safety of CytoSorb

methodsThe proposed intervention involves integrating CytoSorb

Indexed as

CytoSorb®removalrivaroxobanticagrelortrauma

Identifiers

PMID40724567
PMCPMC12299977

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.