Evidence map›Paper›PMID 40724094›Full record

ArticleInternational journal of environmental research and public health2025

Sixteen Years of HPV Vaccination in Mexico: Report of the Coverage, Procurement, and Program Performance (2008-2023).

Rodrigo Romero-Feregrino, Raúl Romero-Cabello, Raúl Romero-Feregrino, Paulina Vilchis-Mora, Berenice Muñoz-Cordero, Mario Alfredo Rodríguez-León

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rodrigo Romero-FeregrinoAsociación Mexicana de Vacunología, Instituto Para el Desarrollo Integral de la Salud (IDISA), Instituto Mexicano del Seguro Social (IMSS), CONCAMIN, Saint Luke School of Medicine, Academia Mexicana de Pediatria, Av. Cuauhtémoc 271, Interior 101, Colonia Roma, Cuauhtémoc, Mexico City ZC 06700, Mexico.ORCID 0000-0001-8489-4221
Raúl Romero-CabelloAsociación Mexicana de Vacunología, Instituto Para el Desarrollo Integral de la Salud (IDISA), Hospital General de México, Department of Microbiology and Parasitology, Universidad Nacional Autónoma de México (UNAM), Saint Luke School of Medicine, Academia Mexicana de Pediatria, Av. Cuauhtémoc 271, Interior 101, Colonia Roma, Cuauhtémoc, Mexico City ZC 06700, Mexico.
Raúl Romero-FeregrinoAsociación Mexicana de Vacunología, Instituto Para el Desarrollo Integral de la Salud (IDISA), UMAE Hospital de Pediatría "Dr. Silvestre Frenk Freund", Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Saint Luke School of Medicine, Academia Mexicana de Pediatria, Av. Cuauhtémoc 271, Interior 101, Colonia Roma, Cuauhtémoc, Mexico City ZC 06700, Mexico.ORCID 0000-0003-1837-7546
Paulina Vilchis-MoraSaint Luke School of Medicine, Sierra Mojada 415, Lomas de Chapultepec III Secc, Miguel Hidalgo, Mexico City ZC 11000, Mexico.
Berenice Muñoz-CorderoAsociación Mexicana de Vacunología, Instituto Para el Desarrollo Integral de la Salud (IDISA), Pediatrics Department/Hospital General de Cuajimalpa IMSS-Bienestar, Av. Cuauhtémoc 271, Interior 101, Colonia Roma, Cuauhtémoc, Mexico City ZC 06700, Mexico.
Mario Alfredo Rodríguez-LeónAsociación Mexicana de Vacunología, Instituto Para el Desarrollo Integral de la Salud (IDISA), Universidad Nacional Autónoma de México (UNAM), Av. Cuauhtémoc 271, Interior 101, Colonia Roma, Cuauhtémoc, Mexico City ZC 06700, Mexico.ORCID 0000-0003-0621-2867

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn 2008, Mexico initiated its national HPV vaccination program targeting adolescent girls. This study aims to evaluate the current status of the program, analyzing trends in vaccine acquisition, administration, and coverage over a 16-year period. MATERIALS AND

methodsA retrospective longitudinal study was conducted using secondary data from 2008 to 2023. Official records from three major public health institutions-IMSS, ISSSTE, and SSA-were reviewed to assess HPV vaccine procurement and administration.

resultsSignificant fluctuations were identified in the number of doses acquired, administered, and the corresponding coverage rates. A marked decline was observed between 2019 and 2021, followed by a sharp increase in 2022 and 2023. Over the entire period, an estimated 6.8 million doses were not administered to the intended target population. Furthermore, 2.6 million doses were administered in excess of the number officially acquired, indicating possible discrepancies in data reporting or vaccine inventory management. DISCUSSION: The findings revealed substantial inconsistencies in vaccine procurement, administration, and coverage across institutions. While IMSS and ISSSTE consistently reported coverage below the theoretical target, SSA occasionally exceeded expectations, potentially compensating for deficits elsewhere. Nevertheless, national coverage remained inadequate in several years, with notable disparities between institutions. These gaps highlight systemic weaknesses in program coordination, planning, and data transparency, contributing to millions of unvaccinated individuals.

conclusionsThis study offers a comprehensive analysis of Mexico's HPV vaccination program, uncovering critical irregularities in its implementation. Challenges include inaccurate target population estimation, inconsistencies between vaccine acquisition and administration, and limited data reliability. Despite some progress in recent years, particularly in the post-pandemic years, the program requires urgent restructuring. This includes implementing a national catch-up strategy, expanding vaccine eligibility, and strengthening surveillance systems to ensure equitable and effective coverage toward the elimination of cervical cancer.

Indexed as

Immunization ProgramsPapillomavirus InfectionsPapillomavirus VaccinesVaccinationVaccination CoverageAdolescentFemaleHumansLongitudinal StudiesMexicoRetrospective StudiesPapillomavirus Vaccinescervical cancer prevention strategiescoveragehealth information systemshealth information systems and data qualityhealth services accessibilityHPV vaccinehuman papilloma virushuman papillomavirus (HPV) vaccinationimmunization program evaluationimmunization programsMexicoMexico/epidemiologypapillomavirus vaccinespublic healthpublic health surveillanceuterine cervical neoplasms/prevention and controlvaccinationvaccination coveragevaccination program performance in Mexicovaccine coverage assessment

Identifiers

PMID40724094
PMCPMC12294797

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.