Evidence map›Paper›PMID 40724024›Full record

ArticleAntibiotics (Basel, Switzerland)2025

Trends in Positive Urine Culture Rates and Antimicrobial Resistance in Non-Hospitalized Children from Western Romania: A Retrospective Observational Study.

Constantin Catalin Marc, Maria Daniela Mot, Monica Licker, Delia Muntean, Daniela Teodora Marti, Ana Alexandra Ardelean, Alina Ciceu, Sergiu Adrian Sprintar, Daniela Adriana Oatis, Alin Gabriel Mihu and 1 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Epidemiological profile of urinary tract infections in children before and during the COVID-19 pandemic: an observational study.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2026
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Constantin Catalin MarcDepartment of General Medicine, Doctoral School, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Maria Daniela MotDepartment of Biology and Life Sciences, Faculty of Medicine, Vasile Goldis Western University of Arad, 310025 Arad, Romania.
Monica LickerMicrobiology Department, Multidisciplinary Research Center of Antimicrobial Resistance, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0002-9245-5883
Delia MunteanMicrobiology Department, Multidisciplinary Research Center of Antimicrobial Resistance, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0001-9100-4530
Daniela Teodora MartiDepartment of Biology and Life Sciences, Faculty of Medicine, Vasile Goldis Western University of Arad, 310025 Arad, Romania.
Ana Alexandra ArdeleanDiscipline of Parasitology, Department of Infectious Diseases, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0001-6235-9076
Alina Ciceu"Aurel Ardelean" Institute of Life Sciences, Vasile Goldis Western University of Arad, 86 Rebreanu, 310414 Arad, Romania.
Sergiu Adrian SprintarCenter for Diagnosis and Study of Parasitic Diseases, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Daniela Adriana OatisCenter for Diagnosis and Study of Parasitic Diseases, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Alin Gabriel MihuDepartment of Biology and Life Sciences, Faculty of Medicine, Vasile Goldis Western University of Arad, 310025 Arad, Romania.ORCID 0000-0001-5218-9026
Tudor Rares OlariuDiscipline of Parasitology, Department of Infectious Diseases, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0002-1094-3729

Funding

"Victor Babes" University of Medicine and Pharmacy Timisoara APC
6 · The paper itself

Abstract

backgroundUrinary tract infections (UTIs) are among the most common types of infections during childhood. Limited data are available on the prevalence of UTI in children from Romania, with most being available for hospitalized children. For this reason, we conducted a retrospective observational study in consecutive non-hospitalized children to assess the number of positive UTI samples and the antibacterial resistance of causative pathogens.

methodsThis study included 7222 consecutive urine cultures collected from children aged 1 to 18 years who are residents of Arad County, Western Romania. Urine samples were analyzed for leukocyturia and cultures for the presence of monomorphic bacteria.

resultsThe overall number of positive UTI samples was 10.44%. A higher number of positive UTI samples was observed in females when compared to males and in children aged 6-12 and 12 to 18 years when compared to those aged 1-5 years. The antibiotic susceptibility testing of

conclusionsGiven the clinical risks associated with UTI in children, our findings underscore the urgent need for the continued monitoring of multidrug-resistant strains. Our study provides important epidemiological and resistance data to guide empirical treatment and strengthen pediatric antimicrobial resistance surveillance. Future studies should focus on different regions and regularly update resistance patterns to keep treatment and prevention strategies aligned with local conditions.

Indexed as

antibiotic resistancechildrenE. coliEscherichia coliRomaniaurinary tract infectionUTI

Identifiers

PMID40724024
PMCPMC12291891

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.