Evidence map›Paper›PMID 40723919›Full record

ArticleBiomolecules2025

The Estimated Intake of S100B Relates to Microbiota Biodiversity in Different Diets.

Tehreema Ghaffar, Veronica Volpini, Serena Platania, Olga Vassioukovitch, Alessandra Valle, Federica Valeriani, Fabrizio Michetti, Vincenzo Romano Spica

Abstract read
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tehreema GhaffarLaboratory of Epidemiology and Biotechnologies, University of Rome "Foro Italico", 00135 Rome, Italy.ORCID 0009-0005-9947-8796
Veronica VolpiniLaboratory of Epidemiology and Biotechnologies, University of Rome "Foro Italico", 00135 Rome, Italy.ORCID 0009-0002-7826-480X
Serena PlataniaGenes Research Start Up, 00187 Rome, Italy.
Olga VassioukovitchGenes Research Start Up, 00187 Rome, Italy.
Alessandra ValleLaboratory of Epidemiology and Biotechnologies, University of Rome "Foro Italico", 00135 Rome, Italy.ORCID 0009-0003-0971-3509
Federica ValerianiLaboratory of Epidemiology and Biotechnologies, University of Rome "Foro Italico", 00135 Rome, Italy.ORCID 0000-0002-9478-6299
Fabrizio MichettiGenes Research Start Up, 00187 Rome, Italy.ORCID 0000-0003-2546-0532
Vincenzo Romano SpicaLaboratory of Epidemiology and Biotechnologies, University of Rome "Foro Italico", 00135 Rome, Italy.ORCID 0000-0002-2900-6399

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The S100B protein, known for its role in the central and enteric nervous systems, has recently been identified in dietary sources such as milk, dairy products, fruits, and vegetables. Given its potential interaction with the gut microbiota, this study explores the relationship between dietary intake of S100B and microbiota biodiversity across different diets. A comprehensive study was conducted, estimating S100B concentrations in 13 dietary patterns recommended in different countries. This is the first study to provide a comparative estimation of S100B exposure from the diet and to explore its potential ecological and epidemiological relevance. The association between S100B levels and microbiota biodiversity was statistically analyzed, showing a direct correlation. Microbial diversity was assessed using the Shannon index, based on data extracted from studies reporting microbiota composition across dietary patterns. Additionally, the relative risk of Crohn's disease was assessed in different populations to examine potential links between dietary patterns, S100B, and chronic disease prevention. A moderate positive correlation (R

Indexed as

DietGastrointestinal MicrobiomeS100 Calcium Binding Protein beta SubunitAdultBiodiversityFemaleHumansMaleS100B protein, humanS100 Calcium Binding Protein beta Subunitchronic disease preventiondietdietary patternsfoodgut microbiotaS100BShannon index

Identifiers

PMID40723919
PMCPMC12292894

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.