Evidence map›Paper›PMID 40723811›Full record

ArticleBiomolecules2025

β-Secosterol, an Oxyphytosterol Produced Through the Reaction of β-Sitosterol with Ozone, Demonstrates Different Cytotoxic Effects on BRL-3A and HTC Cells.

Bianca S Takayasu, Igor R Martins, Miriam Uemi, Janice Onuki, Glaucia M Machado-Santelli

Abstract read
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bianca S TakayasuDepartment of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.ORCID 0000-0002-8036-7181
Igor R MartinsDepartment of Chemistry, Institute of Environmental, Chemical and Pharmaceutical Sciences, Federal University of São Paulo, São Paulo 09972-270, Brazil.ORCID 0000-0002-6104-5080
Miriam UemiDepartment of Chemistry, Institute of Environmental, Chemical and Pharmaceutical Sciences, Federal University of São Paulo, São Paulo 09972-270, Brazil.
Janice OnukiLaboratory of Structural Biology, Butantan Institute, São Paulo 05503-900, Brazil.ORCID 0000-0001-5343-8848
Glaucia M Machado-SantelliDepartment of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 00Financiadora de Estudos e Projetos 00Fundação Butantan 00Fundação de Amparo à Pesquisa do Estado de São Paulo 2014/14801-8Fundação de Amparo à Pesquisa do Estado de São Paulo 2015/17177-6Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/19506-8National Council for Scientific and Technological Development 316504/2021National Council for Scientific and Technological Development 440472/2022-91National Council for Scientific and Technological Development 484628/2013-5
6 · The paper itself

Abstract

Sitosterol (Sito) is a phytosterol with bioactive properties, including reducing atherosclerosis risk and anti-inflammatory and antitumoral effects. However, it can be oxidized by reactive oxygen species such as ozone (O

Indexed as

OzonePhytosterolsSitosterolsAnimalsCell CycleCell LineCell SurvivalHep G2 CellsHumansRatsgamma-sitosterolOzonePhytosterolsSitosterolscell cyclecytoskeletonoxyphytosterolsozonesitosterolβ-secosterol

Identifiers

PMID40723811
PMCPMC12292371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.