Evidence map›Paper›PMID 40723806›Full record

ArticleBiomolecules2025

The Synthesis, Characterization, and Biological Evaluation of a Fluorenyl-Methoxycarbonyl-Containing Thioxo-Triazole-Bearing Dipeptide: Antioxidant, Antimicrobial, and BSA/DNA Binding Studies for Potential Therapeutic Applications in ROS Scavenging and Drug Transport.

Lala Stepanyan, Tatevik Sargsyan, Valentina Mittova, Zurab R Tsetskhladze, Nino Motsonelidze, Ekaterine Gorgoshidze, Niccolò Nova, Monika Israyelyan, Hayarpi Simonyan, Franco Bisceglie and 3 more

Abstract read
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lala StepanyanScientific and Production Center "Armbiotechnology" NAS RA, 14 Gyurjyan Str., Yerevan 0056, Armenia.
Tatevik SargsyanScientific and Production Center "Armbiotechnology" NAS RA, 14 Gyurjyan Str., Yerevan 0056, Armenia.ORCID 0000-0001-6275-0665
Valentina MittovaFaculty of Medicine, University Geomedi, 4 King Solomon II Str., 0114 Tbilisi, Georgia.ORCID 0000-0002-9844-8684
Zurab R TsetskhladzeFaculty of Medicine, University Geomedi, 4 King Solomon II Str., 0114 Tbilisi, Georgia.
Nino MotsonelidzeFaculty of Medicine, University Geomedi, 4 King Solomon II Str., 0114 Tbilisi, Georgia.
Ekaterine GorgoshidzeFaculty of Medicine, University Geomedi, 4 King Solomon II Str., 0114 Tbilisi, Georgia.
Niccolò NovaDepartment of Chemical Science, Life and Environmental Sustainability, University of Parma, Parco Area delle Scienze 17/A, 43124 Parma, Italy.ORCID 0009-0004-9514-7685
Monika IsrayelyanScientific and Production Center "Armbiotechnology" NAS RA, 14 Gyurjyan Str., Yerevan 0056, Armenia.
Hayarpi SimonyanInstitute of Pharmacy, Yerevan State University, 1 Alex Manoogian Str., Yerevan 0025, Armenia.
Franco BisceglieDepartment of Chemical Science, Life and Environmental Sustainability, University of Parma, Parco Area delle Scienze 17/A, 43124 Parma, Italy.ORCID 0000-0001-9165-0356
Lusine SahakyanScientific and Production Center "Armbiotechnology" NAS RA, 14 Gyurjyan Str., Yerevan 0056, Armenia.ORCID 0000-0001-7244-184X
Karapet GhazaryanInstitute of Pharmacy, Yerevan State University, 1 Alex Manoogian Str., Yerevan 0025, Armenia.
Giovanni N RovielloInstitute of Biostructures and Bioimaging (IBB), Italian National Council for Research (CNR), Area di Ricerca Site and Headquarters, Via Pietro Castellino 111, 80131 Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report on the synthesis and characterization of a novel fluorenyl-methoxycarbonyl (Fmoc)-containing thioxo-triazole-bearing dipeptide

Indexed as

Anti-Infective AgentsAntioxidantsDipeptidesDNASerum Albumin, BovineTriazolesAnimalsCattleCircular DichroismMolecular Docking SimulationReactive Oxygen SpeciesAnti-Infective AgentsAntioxidantscalf thymus DNADipeptidesDNAReactive Oxygen SpeciesSerum Albumin, BovineTriazolesantimicrobial activityantioxidant propertiesbioactive peptidesbovine serum albuminBSACaucasus-endemic plantsDNA modulationfluorenyl-methoxycarbonylfmocthioxo-triazole

Identifiers

PMID40723806
PMCPMC12292336

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.