Evidence map›Paper›PMID 40723658›Full record

ArticleBehavioral sciences (Basel, Switzerland)2025

Helping Opioid Use Disorder and PTSD with Exposure (HOPE): An Open-Label Pilot Study of a Trauma-Focused, Integrated Therapy for OUD/PTSD.

Tanya C Saraiya, Sonali Singal, Krithika Prakash, Priya Johal, Sara Hameed, Sudie E Back, Katherine L Mills, Denise A Hien

Abstract read
In one paragraph

Article in Behavioral sciences (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tanya C SaraiyaDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0002-8910-947X
Sonali SingalDepartment of Clinical Psychology, Rutgers University-New Brunswick, New Brunswick, NJ 08854, USA.ORCID 0000-0001-9937-6224
Krithika PrakashDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15260, USA.ORCID 0000-0002-9850-4332
Priya JohalCanadian Institute for Substance Use Research, University of Victoria, Victoria, BC V8P 5C2, Canada.ORCID 0009-0002-2048-6637
Sara HameedDepartment of Clinical Psychology, Rutgers University-New Brunswick, New Brunswick, NJ 08854, USA.ORCID 0009-0001-7314-9725
Sudie E BackDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0002-7683-8737
Katherine L MillsThe Matilda Centre, University of Sydney, Camperdown, NSW 2050, Australia.ORCID 0000-0002-9714-1832
Denise A HienDepartment of Clinical Psychology, Rutgers University-New Brunswick, New Brunswick, NJ 08854, USA.ORCID 0000-0002-6954-2882

Funding

Translational Research Training on Addictions for Racial/Ethnic MinoritiesR25DA035161 · NIDA · CITY COLLEGE OF NEW YORK · PI DENISE AIMEE HIEN, Lesia Monique Ruglass · 2013 to 2026
$4.4M
Integrated Treatment for Co-Occurring Opioid Use Disorder and Posttraumatic Stress DisorderK23DA055209 · NIDA · RUTGERS, THE STATE UNIV OF N.J. · PI Tanya Chandresh Saraiya · 2022 to 2026
$1.1M
NIDA NIH HHS K23 DA055209NIDA NIH HHS R25 DA035161NIH HHS 1K23DA055209
6 · The paper itself

Abstract

Opioid use disorder (OUD) and posttraumatic stress disorder (PTSD) frequently co-occur. However, there are no psychotherapy treatments intentionally designed for this comorbidity, nor designed to be augmented with medications for OUD. In this open-label pilot trial, we tested Helping Opioid Use Disorder and PTSD with Exposure (HOPE), a novel integrated, trauma-focused treatment for individuals (

Indexed as

exposure therapyintegrated treatmentopioid use disorderposttraumatic stress disorder (PTSD)

Identifiers

PMID40723658
PMCPMC12292416

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.