Evidence map›Paper›PMID 40723563›Full record

ArticleAnimals : an open access journal from MDPI2025

The Role of Gonadotropins and Growth Factor in Regulating Ras During Maturation in Cumulus-Oocyte Complexes of Pigs.

Eunju Seok, Minyoung Son, Seunghyung Lee, Hee-Tae Cheong, Sang-Hee Lee

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eunju SeokCollege of Animal Life Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea.
Minyoung SonCollege of Animal Life Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea.
Seunghyung LeeCollege of Animal Life Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea.ORCID 0000-0001-5862-3663
Hee-Tae CheongCollege of Veterinary Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea.
Sang-Hee LeeCollege of Animal Life Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea.ORCID 0000-0001-8725-4174

Funding

Ministry of Science and ICT IIPT-2025-RS-2023-00260267
6 · The paper itself

Abstract

Oocytes and cumulus cells undergo meiotic resumption and proliferation via gonadotropins and growth factors during maturation, and various small G proteins are activated when COCs undergo physiological changes. This study investigated the influence of gonadotropins and growth factors on Ras and its GTPases during porcine COC maturation. Unmatured COCs were treated with FSH, LH, or EGF for 44 h. The mRNA expression levels of the Ras subfamily (

Indexed as

cumulus–oocyte complexesgonadotropinmaturationRasRas GTPase

Identifiers

PMID40723563
PMCPMC12291885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.