Evidence map›Paper›PMID 40723280›Full record

ArticleCancers2025

Genes Encoding Multiple Modulators of the Immune Response Are Methylated in the Prostate Tumor Microenvironment of African Americans.

Vinay Kumar, Tara Sinta Kartika Jennings, Lucas Ueta, James Nguyen, Liankun Song, Michael McClelland, Weiping Chu, Michael Lilly, Michael Ittmann, Patricia Castro and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Vinay KumarDepartment of Pathology and Laboratory Medicine, University of California, Irvine, CA 92697, USA.
Tara Sinta Kartika JenningsDepartment of Pathology and Laboratory Medicine, University of California, Irvine, CA 92697, USA.
Lucas UetaDepartment of Pathology and Laboratory Medicine, University of California, Irvine, CA 92697, USA.
James NguyenDepartment of Pathology and Laboratory Medicine, University of California, Irvine, CA 92697, USA.
Liankun SongDepartment of Urology, University of California, Irvine, CA 92697, USA.
Michael McClellandDepartment of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697, USA.
Weiping ChuDepartment of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697, USA.
Michael LillyDepartment of Medicine, Division of Hematology and Oncology, Medical University of South Carolina (MUSC), Charleston, SC 29425, USA.
Michael IttmannDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
Patricia CastroDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0001-5286-8037
Arash Rezazadeh KalebastyDivision of Hematology and Oncology, University of California, Irvine, CA 92697, USA.ORCID 0000-0002-3701-5084
Dan MercolaDepartment of Pathology and Laboratory Medicine, University of California, Irvine, CA 92697, USA.
Omid YazdanpanahDivision of Hematology and Oncology, University of California, Irvine, CA 92697, USA.ORCID 0000-0002-5795-461X
Xiaolin ZiDepartment of Urology, University of California, Irvine, CA 92697, USA.
Farah RahmatpanahDepartment of Pathology and Laboratory Medicine, University of California, Irvine, CA 92697, USA.

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Suzanne AW Fuqua · 2007 to 2026
$73.9M
Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
Human Endogenous retroviruses as potential early markers for Alzheimer's diseaseR01CA226570 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI RAHMATPANAH, FARAH BAKHSHIAN · 2019 to 2023
$2.2M
Ethnicity-determined T cell responses and GARP/TGFbeta1 signaling in prostate cancerR01CA260351 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Anshu Agrawal, Xiaolin Zi · 2022 to 2026
$1.8M
BLRD VA I01 BX005105BLRD VA I01 BX005597NCI NIH HHS P30 CA062203NCI NIH HHS P30 CA125123NCI NIH HHS R01 CA226570NCI NIH HHS R01 CA260351NIH HHS 1R01CA226570-25
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

African AmericanDNA methylationEuropean Americanprostate cancertumor microenvironment

Identifiers

PMID40723280
PMCPMC12293404

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.