Evidence map›Paper›PMID 40723108›Full record

ReviewChildren (Basel, Switzerland)2025

Main Processed Hypoallergenic Foods: A Potential Tool to Improve Informed Dietary Choices in Children with IgE-Mediated Food Allergies.

Luca Pecoraro, Simona Barni, Francesca Mori, Mattia Giovannini, Riccardo Castagnoli, Stefania Arasi, Carla Mastrorilli, Francesca Saretta, Lucia Liotti, Lucia Caminiti and 5 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Luca PecoraroPediatric Unit, Ospedale Vito Fazzi, ASL Lecce, 73100 Lecce, Italy.ORCID 0000-0002-9765-8006
Simona BarniAllergy Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.ORCID 0000-0001-5598-2740
Francesca MoriAllergy Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.
Mattia GiovanniniAllergy Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.ORCID 0000-0001-9568-6882
Riccardo CastagnoliDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-0029-9383
Stefania ArasiTranslational Research in Pediatric Specialties Area, Division of Allergy, Bambino Gesù Children's Hospital [IRCCS], 00165 Rome, Italy.ORCID 0000-0002-8135-0568
Carla MastrorilliPediatric and Emergency Department, Pediatric Hospital Giovanni XXIII, AOU Policlinic of Bari, 70126 Bari, Italy.
Francesca SarettaPediatric Department, Latisana-Palmanova Hospital, Azienda Sanitaria Universitaria Friuli Centrale, 33100 Udine, Italy.ORCID 0000-0001-9443-5483
Lucia LiottiPediatric Unit, Department of Mother and Child Health, Salesi Children's Hospital, 60123 Ancona, Italy.
Lucia CaminitiPediatric Unit, Department of Human Pathology in Adult and Development Age "Gaetano Barresi", Allergy Unit, AOU Policlinico Gaetano Martino, 98124 Messina, Italy.
Angela KlainDepartment of Woman, Child and of General and Specialized Surgery, University of Campania 'Luigi Vanvitelli', 80138 Naples, Italy.ORCID 0000-0001-7823-2125
Mariannita GelsominoAllergy Unit, Pediatrics Area, Department of Woman and Child Health, Policlinico Gemelli University Foundation IRCCS, Catholic University of Sacre Hearth, 00168 Rome, Italy.
Michele Miraglia Del GiudiceDepartment of Woman, Child and of General and Specialized Surgery, University of Campania 'Luigi Vanvitelli', 80138 Naples, Italy.ORCID 0000-0002-8369-5957
Gian Luigi MarsegliaDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.
Elio NovembreDepartment of Health Sciences, University of Florence, 50139 Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the context of IgE-mediated food allergies in children, the use of hypoallergenic foods may offer an appropriate solution for enabling informed dietary choices and reducing reactivity to allergenic foods. It is well established that certain foods can alter their allergenicity depending on the method of processing. As such, processed foods may serve both as an alternative dietary option and as a useful tool in oral immunotherapy for children with IgE-mediated food allergies. Nevertheless, an oral food challenge is always recommended when a pediatric allergist considers incorporating processed foods into a child's diet. This review aims to explore the potential use of processed forms of the nine major food allergens in IgE-mediated food allergies, supporting pediatric allergists in partially liberalizing children's diets and facilitating the development of tolerance.

Indexed as

allergenic foodsbig 9food allergyoral allergen immunotherapyprocessed foodsprocessed forms of food allergensprocessing method

Identifiers

PMID40723108
PMCPMC12294083

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.