Evidence map›Paper›PMID 40723021›Full record

ArticleChildren (Basel, Switzerland)2025

Continuous Renal Replacement Therapy in Critically-Ill Term and Preterm Newborns: A Single-Center Study in Belgrade.

Snezana Rsovac, Katarina Milosevic, Brankica Spasojevic, Mirjana Cvetkovic, Gordana Milosevski Lomic, Biljana Medjo, Mina G Cobeljic, Nadja Vukasinovic, Vesna Selakovic, Dusan Todorovic and 3 more

Abstract read
In one paragraph

Article in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Snezana RsovacDepartment of Pediatric and Neonatal Intensive Care, University Children's Hospital, Tirsova 10, 11000 Belgrade, Serbia.ORCID 0000-0002-9987-057X
Katarina MilosevicFaculty of Medicine, University of Belgrade, Dr. Subotića 8, 11000 Belgrade, Serbia.
Brankica SpasojevicFaculty of Medicine, University of Belgrade, Dr. Subotića 8, 11000 Belgrade, Serbia.
Mirjana CvetkovicFaculty of Medicine, University of Belgrade, Dr. Subotića 8, 11000 Belgrade, Serbia.
Gordana Milosevski LomicFaculty of Medicine, University of Belgrade, Dr. Subotića 8, 11000 Belgrade, Serbia.ORCID 0000-0002-6601-1955
Biljana MedjoDepartment of Pediatric and Neonatal Intensive Care, University Children's Hospital, Tirsova 10, 11000 Belgrade, Serbia.ORCID 0000-0003-0060-427X
Mina G CobeljicDepartment of Pediatric and Neonatal Intensive Care, University Children's Hospital, Tirsova 10, 11000 Belgrade, Serbia.ORCID 0000-0003-1655-8714
Nadja VukasinovicDepartment of Pediatric and Neonatal Intensive Care, University Children's Hospital, Tirsova 10, 11000 Belgrade, Serbia.ORCID 0009-0007-2682-2984
Vesna SelakovicDepartment of Pediatric and Neonatal Intensive Care, University Children's Hospital, Tirsova 10, 11000 Belgrade, Serbia.
Dusan TodorovicInstitute of Medical Physiology "Richard Burian", Faculty of Medicine, University of Belgrade, Visegradska 26, 11000 Belgrade, Serbia.ORCID 0000-0002-8270-3089
Masa PetrovicInstitute for Cardiovascular Diseases "Dedinje", Heroja Milana Tepića 1, 11000 Belgrade, Serbia.ORCID 0000-0003-1709-8449
Davor PlavecPRIMA NOVA, Healthcare Institution, 10090 Zagreb, Croatia.
Jasna KalanjDepartment of Pediatric and Neonatal Intensive Care, University Children's Hospital, Tirsova 10, 11000 Belgrade, Serbia.ORCID 0000-0002-8663-9010

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesContinuous renal replacement therapy (CRRT) is an important treatment method that is becoming a commonly-used procedure in neonatal intensive care units (NICUs), especially in critically-ill neonates.

methodsWe conducted a retrospective study aimed to evaluate factors influencing the outcomes of CRRT in neonates and preterm infants. The study analyzed data from 41 newborns treated with CRRT at our NICU over a ten-year period. Demographic, clinical, and laboratory parameters were assessed, including gestational age, birth weight, PRISM III score, and laboratory markers like urea, creatinine, and potassium levels, as well as characteristics of CRRT.

resultsOur research found that the duration of CRRT, the presence of anuria, and higher potassium levels after initiation of CRRT were significant predictors of a poor outcome. Despite the lack of significant correlation between demographic characteristics, PRISM III score and the outcome, our findings highlight the importance of timely CRRT initiation and efficient management to improve survival.

conclusionsOur study identified several significant prognostic indicators in neonates undergoing renal replacement therapy. While these findings provide valuable insights, further research is needed to establish clear theoretical guidelines and improve clinical decision-making.

Indexed as

continuous renal replacement therapydialysisneonatesprognostic factors

Identifiers

PMID40723021
PMCPMC12293272

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.