Evidence map›Paper›PMID 40723002›Full record

ArticleChildren (Basel, Switzerland)2025

Biochemical Effects of Long-Term Exercise on Oxidative Stress and Antioxidant Markers in Adolescent Female Athletes.

Ömer Faruk Bilici, Dilara Erkan, Dan Iulian Alexe, Dragoș Ioan Tohănean, Canan Demir, Cristina Ioana Alexe, Virgil Ene Voiculescu, Muhammed Fatih Bilici, Héctor Fuentes-Barria, Ulas Can Yildirim

Abstract read
In one paragraph

Article in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Acute Effects ofFoods (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ömer Faruk BiliciDepartment of Sport Sciences, Institute of Health Sciences, Marmara University, Kartal, İstanbul 34865, Türkiye.ORCID 0000-0002-8679-4715
Dilara ErkanDepartment of Physical Education and Sports, Institute of Health Sciences, Ankara University, Gölbaşı, Ankara 06830, Türkiye.ORCID 0000-0002-2403-4841
Dan Iulian AlexeDepartment of Physical and Occupational Therapy, "Vasile Alecsandri" University of Bacău, 600115 Bacău, Romania.ORCID 0000-0002-6396-761X
Dragoș Ioan TohăneanFaculty of Physical Education and Mountain Sports, Transilvania University of Brașov, 500036 Brasov, Romania.ORCID 0000-0002-6740-1867
Canan DemirDepartment of Medical Services and Techniques, Van Health Services Vocational School, Van Yuzuncu Yil University, Tuşba, Van 65090, Türkiye.ORCID 0000-0002-4204-9756
Cristina Ioana AlexeDepartment of Physical Education and Sports Performance, "Vasile Alecsandri" University of Bacău, 600115 Bacău, Romania.ORCID 0000-0001-7424-7741
Virgil Ene VoiculescuNaval Tactics and Armament Department, Faculty of Marine Engineering, Mircea cel Batran Naval Academy, 900218 Constanta, Romania.ORCID 0000-0002-1451-207X
Muhammed Fatih BiliciDepartment of Coaching Education, Faculty of Sport Sciences, Muş Alparslan University, Suvaran, Muş 49160, Türkiye.
Héctor Fuentes-BarriaVicerrectoría de Investigación e Innovación, Universidad Arturo Prat, Iquique 1110939, Chile.ORCID 0000-0003-0774-0848
Ulas Can YildirimDepartment of Coaching Education, Faculty of Sport Sciences, Sinop University, Osmaniye, Sinop 57100, Türkiye.ORCID 0000-0001-7767-8416

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdolescence is a critical period where exercise-induced oxidative stress is modulated by both training adaptations and hormonal changes, particularly the antioxidant effects of estrogen in females. However, data on how adolescent female athletes respond to long-term exercise remain limited. The aim of this study was to examine oxidative stress levels and some antioxidant defense parameters in adolescent female athletes who train regularly.

methodsThe study included 20 adolescent female basketball players (16.65 ± 0.67 years; 165.50 ± 0.06 cm; 59.75 ± 5.50 kg) with at least three years of training experience and 20 non-athlete adolescent female participants (16.80 ± 0.69 years; 159.95 ± 0.04 cm; 60.15 ± 4.23 kg). Malondialdehyde (MDA), glutathione (GSH), and catalase (CAT) levels were analyzed by a spectrophotometric method using a UV/VIS spectrophotometer in blood samples taken from all participants, and the data were compared between the groups.

resultsThe results showed that MDA levels were significantly lower in the athlete group (

conclusionsThese findings suggest that prolonged exercise reduces oxidative stress and enhances catalase-mediated antioxidant defense in adolescent women. Increased CAT activity and decreased MDA levels support this effect, while stable GSH levels point to the role of compensatory mechanisms.

Indexed as

adolescentantioxidantsathletesexercisefemaleoxidative stress

Identifiers

PMID40723002
PMCPMC12293437

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.