Evidence map›Paper›PMID 40722926›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Galangin Regulates Oxidative Stress Levels in Porcine Embryos Through Interaction with the Neh1 Domain of Nrf2.

Zhi-Chao Chi, Shu-Ming Shi, Li-Ying Liu, Lin-Yi Qu, Jing-Hang Li, Guan-Lin Jia, Yu-Yan He, Lin-Xuan Li, Yong-Xun Jin, Ming-Jun Zhang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhi-Chao ChiCollege of Animal Sciences, Jilin University, Changchun 130062, China.
Shu-Ming ShiCollege of Animal Sciences, Jilin University, Changchun 130062, China.ORCID 0009-0007-0594-8000
Li-Ying LiuCollege of Animal Sciences, Jilin University, Changchun 130062, China.
Lin-Yi QuCollege of Animal Sciences, Jilin University, Changchun 130062, China.
Jing-Hang LiCollege of Animal Sciences, Jilin University, Changchun 130062, China.
Guan-Lin JiaCollege of Animal Sciences, Jilin University, Changchun 130062, China.
Yu-Yan HeCollege of Animal Sciences, Jilin University, Changchun 130062, China.
Lin-Xuan LiCollege of Animal Sciences, Jilin University, Changchun 130062, China.
Yong-Xun JinCollege of Animal Sciences, Jilin University, Changchun 130062, China.
Ming-Jun ZhangCollege of Animal Sciences, Jilin University, Changchun 130062, China.
Xian-Feng YuCollege of Animal Sciences, Jilin University, Changchun 130062, China.ORCID 0000-0003-0589-2178

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress poses a challenge to in vitro embryo culture. As a flavonoid, galangin (GAL) has been shown to have antioxidant effects, but the effect and antioxidant capacity of GAL in the in vitro development of porcine parthenogenetic embryos are still unknown. In this study, we demonstrated that 1 µM GAL significantly increased the blastocyst rate, decreased the accumulation of intracellular reactive oxygen species (ROS), increased the glutathione (GSH) level, and enhanced mitochondrial function in early porcine embryos. Nuclear factor erythroid-2-related factor 2 (

Indexed as

galanginIVCmitochondriaNrf2oxidative stresspreimplantation embryo

Identifiers

PMID40722926
PMCPMC12291769

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.