Evidence map›Paper›PMID 40722917›Full record

ArticleAntioxidants (Basel, Switzerland)2025

The Naturally Bioactive Vicine Extracted from Faba Beans Is Responsible for the Transformation of Grass Carp (

Xinyu Zheng, Minyi Luo, Bing Fu, Gen Kaneko, Jingjing Tian, Jun Xie, Jilun Hou, Ermeng Yu

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xinyu ZhengState Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao 066100, China.ORCID 0009-0004-0687-4355
Minyi LuoAgricultural Service Center of Xiaolan Town, Zhongshan 528415, China.
Bing FuCollege of Marine Sciences, South China Agricultural University, Guangzhou 510640, China.
Gen KanekoCollege of Natural and Applied Science, University of Houston-Victoria, Victoria, TX 77901, USA.ORCID 0000-0003-4295-5123
Jingjing TianKey Laboratory of Tropical and Subtropical Fishery Resources Application and Cultivation, Ministry of Agriculture and Rural Affairs, Pearl River Fisheries Research Institute Chinese Academy of Fishery Sciences, Guangzhou 510380, China.ORCID 0000-0002-0948-289X
Jun XieKey Laboratory of Tropical and Subtropical Fishery Resources Application and Cultivation, Ministry of Agriculture and Rural Affairs, Pearl River Fisheries Research Institute Chinese Academy of Fishery Sciences, Guangzhou 510380, China.
Jilun HouState Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao 066100, China.ORCID 0000-0003-1370-822X
Ermeng YuKey Laboratory of Tropical and Subtropical Fishery Resources Application and Cultivation, Ministry of Agriculture and Rural Affairs, Pearl River Fisheries Research Institute Chinese Academy of Fishery Sciences, Guangzhou 510380, China.ORCID 0000-0001-6348-9884

Funding

Central Public-interest Scientific Institution Basal Research Fund CAFS, NO. 2021XT03Guangdong Basic and Applied Basic Research Foundation 2021A1515011178Key Laboratory of Tropical and Subtropical Fishery Resources Application and Cultivation, Ministry of Agriculture and Rural Affairs 20230202Ministry of Agriculture and Rural Affairs, the Modern Agro-industry Technology Research System No. CARS-45-21the Social Welfare and Basic Research Project of Zhongshan City, Guangdong Province, China 2021B2013
6 · The paper itself

Abstract

While faba bean feeding improves grass carp muscle texture via reactive oxygen species (ROS), the main bioactive compound was unclear. In this study, vicine-a pro-oxidant glycoside-was isolated from faba beans using cation-exchange column chromatography and supplemented into the feed of grass carp at 0.6%. To assess the impact of vicine on muscle texture, the grass carp were fed for 150 days with three treatments: control group, faba bean group, and vicine group. The results showed that vicine improved muscle texture similarly to faba beans but caused fewer adverse effects on muscle, liver, and intestinal health. Vicine improved grass carp muscle texture in the following ways: (1) induced ROS overproduction, activating the Caspase apoptosis pathway and downregulating

Indexed as

grass carpoxidant stressreactive oxygen speciestextural qualityvicine

Identifiers

PMID40722917
PMCPMC12291655

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.