Evidence map›Paper›PMID 40722849›Full record

ReviewBiomedicines2025

Radiomics and Radiogenomics in Differentiating Progression, Pseudoprogression, and Radiation Necrosis in Gliomas.

Sohil Reddy, Tyler Lung, Shashank Muniyappa, Christine Hadley, Benjamin Templeton, Joel Fritz, Daniel Boulter, Keshav Shah, Raj Singh, Simeng Zhu and 2 more

Abstract readReview
In one paragraph

Review in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sohil ReddyCollege of Medicine, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-3746-6424
Tyler LungCollege of Medicine, The Ohio State University, Columbus, OH 43210, USA.
Shashank MuniyappaCollege of Medicine, The Ohio State University, Columbus, OH 43210, USA.
Christine HadleyCollege of Medicine, The Ohio State University, Columbus, OH 43210, USA.ORCID 0009-0001-1651-6656
Benjamin TempletonCollege of Medicine, The Ohio State University, Columbus, OH 43210, USA.
Joel FritzDepartment of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Daniel BoulterDepartment of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Keshav ShahCollege of Public Health, The Ohio State University, Columbus, OH 43210, USA.
Raj SinghDepartment of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Simeng ZhuDepartment of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Jennifer K MatsuiDepartment of Radiation Oncology, Stanford Medicine, Stanford, CA 94305, USA.
Joshua D PalmerDepartment of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.ORCID 0000-0003-3311-0129

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over recent decades, significant advancements have been made in the treatment and imaging of gliomas. Conventional imaging techniques, such as MRI and CT, play critical roles in glioma diagnosis and treatment but often fail to distinguish between tumor pseudoprogression (Psp) and radiation necrosis (RN) versus true progression (TP). Emerging fields like radiomics and radiogenomics are addressing these challenges by extracting quantitative features from medical images and correlating them with genomic data, respectively. This article will discuss several studies that show how radiomic features (RFs) can aid in better patient stratification and prognosis. Radiogenomics, particularly in predicting biomarkers such as

Indexed as

glioblastomagliomapseudoprogressionradiation necrosisradiogenomicsradiomicstumor progressiontumor recurrence

Identifiers

PMID40722849
PMCPMC12292999

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.