Evidence map›Paper›PMID 40722741›Full record

ArticleBiomedicines2025

Involvement of Microglia in Retinal Ganglion Cell Injury Induced by IOP Elevation in a Rat Ex Vivo Acute Glaucoma Model.

Taimu Sato, Makoto Ishikawa, Yukitoshi Izumi, Naoya Shibata, Kota Sato, Michiko Ohno-Oishi, Hiroshi Tawarayama, Hiroshi Kunikata, Charles F Zorumski, Toru Nakazawa

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Taimu SatoDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Makoto IshikawaDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Yukitoshi IzumiTaylor Family Institute for Innovative Psychiatric Research, Washington University School of Medicine, St. Louis, MO 63110, USA.
Naoya ShibataAoba Eye Clinic, Akita 010-1413, Japan.
Kota SatoDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Michiko Ohno-OishiDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Hiroshi TawarayamaDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.ORCID 0000-0001-8696-6700
Hiroshi KunikataDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Charles F ZorumskiTaylor Family Institute for Innovative Psychiatric Research, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-9704-5154
Toru NakazawaDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.

Funding

the JST COI-NEXT JPMJPF2201, the JSPS KAKENHI Grants-in-Aid for Scientific Research C to MI 22K09827
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

glaucomainterleukin-1βintraocular pressureneuroinflammationneuroprotectionNLRP3 inflammasomePLX5622

Identifiers

PMID40722741
PMCPMC12292869

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.