Evidence map›Paper›PMID 40722732›Full record

ArticleBiomedicines2025

Targeting CDK4/6 in Cancer: Molecular Docking and Cytotoxic Evaluation of

Maruthamuthu Rathinam Elakkiya, Mohandas Krishnasreya, Sureshkumar Tharani, Muthukrishnan Arun, L Vijayalakshmi, Jiseok Lim, Ayman A Ghfar, Balasundaramsaraswathy Chithradevi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maruthamuthu Rathinam ElakkiyaDepartment of Botany, PSGR Krishnammal College for Women, Coimbatore 641004, Tamil Nadu, India.ORCID 0009-0004-8001-3203
Mohandas KrishnasreyaDepartment of Botany, PSGR Krishnammal College for Women, Coimbatore 641004, Tamil Nadu, India.ORCID 0009-0001-3311-6638
Sureshkumar TharaniGRG BIRAC EYUVA Centre, PSGR Krishnammal College for Women, Coimbatore 641004, Tamil Nadu, India.ORCID 0009-0000-9898-3225
Muthukrishnan ArunDepartment of Biotechnology, Bharathiar University, Coimbatore 641046, Tamil Nadu, India.ORCID 0000-0002-0120-2988
L VijayalakshmiDepartment of Mechanical Engineering, Yeungnam University, Gyeongsan-si 38541, Republic of Korea.
Jiseok LimDepartment of Mechanical Engineering, Yeungnam University, Gyeongsan-si 38541, Republic of Korea.
Ayman A GhfarDepartment of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-6685-7918
Balasundaramsaraswathy ChithradeviDepartment of Botany, PSGR Krishnammal College for Women, Coimbatore 641004, Tamil Nadu, India.ORCID 0000-0002-6205-9556

Funding

King Saud University, Riyadh, Saudi Arabia RSP2025R407National Research Foundation of Korea (NRF), funded by the Ministry of Education NRF-2021R1A6A1A03039493 & NRF-2022R1A2C1009389
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ADME profilingCDK4/6 inhibitioncell migrationcytotoxicitymolecular dockingThottea siliquosa

Identifiers

PMID40722732
PMCPMC12292890

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.