Evidence map›Paper›PMID 40722615›Full record

ArticleBiomedicines2025

Betulinic Acid ω-Triphenylphosphonium Alkyl Esters: Antiproliferative Activities and In Silico Pharmacokinetic Profiles.

Cristian Suárez-Rozas, Claudia Duarte-Salinas, Javier Gajardo-De la Fuente, Paola Salgado-Figueroa, Julio Salas-Norambuena, Bruce K Cassels, Cristina Theoduloz, José A Jara, Sebastián Fuentes-Retamal, Paola R Campodónico and 2 more

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cristian Suárez-RozasCentro de Química Médica, Instituto de Ciencias e Innovación en Medicina, Facultad de Medicina, Clínica Alemana Universidad del Desarrollo, Santiago 7610658, Chile.
Claudia Duarte-SalinasCentro de Química Médica, Instituto de Ciencias e Innovación en Medicina, Facultad de Medicina, Clínica Alemana Universidad del Desarrollo, Santiago 7610658, Chile.
Javier Gajardo-De la FuenteFaculty of Chemical and Pharmaceutical Sciences, University of Chile, Santiago 8330015, Chile.
Paola Salgado-FigueroaFaculty of Chemical and Pharmaceutical Sciences, University of Chile, Santiago 8330015, Chile.
Julio Salas-NorambuenaDepartment of Chemistry, Faculty of Sciences, University of Chile, Santiago 7800003, Chile.
Bruce K CasselsDepartment of Chemistry, Faculty of Sciences, University of Chile, Santiago 7800003, Chile.ORCID 0000-0002-0082-0661
Cristina TheodulozCell Culture Laboratory, Faculty of Health Sciences, University of Talca, Talca 3480094, Chile.
José A JaraPharmacology Laboratory, ICOD, Institute for Dental Research, Faculty of Dentistry, University of Chile, Santiago 8330111, Chile.
Sebastián Fuentes-RetamalEscuela de Química y Farmacia, Facultad de Medicina, Universidad Andrés Bello, Santiago 8320000, Chile.ORCID 0000-0002-3944-3138
Paola R CampodónicoCentro de Química Médica, Instituto de Ciencias e Innovación en Medicina, Facultad de Medicina, Clínica Alemana Universidad del Desarrollo, Santiago 7610658, Chile.ORCID 0000-0003-2840-0666
Jorge Soto-DelgadoDepartamento de Ciencias Químicas, Facultad de Ciencias Exactas, Universidad Andrés Bello, Viña del Mar 2531015, Chile.ORCID 0000-0002-2983-1727
Mabel CatalánMolecular and Clinical Program, Biomedical Science Institute (ICBM), Faculty of Medicine, Universidad de Chile, Santiago 8330111, Chile.

Funding

Fondo Nacional para el Desarrollo Científico y Tecnológico (FONDECYT) Postdoctoral grant 3220509 (C.S-R.)PhD scholarship through ANID-PFCHA 21202560 (J.S.-N.)Proyecto Puente ICBM-2023 Non Apply (M.C.)research program PIEI-QUIM-BIO, University of Talca Non Apply (C.T.)
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antiproliferative activitiesbetulinic acid derivativescancerdrugs discoverynatural productssynthetic strategy

Identifiers

PMID40722615
PMCPMC12292992

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.