Increasing Nebulizer Spray Efficiency Using a Baffle with a Conical Surface: A Computational Fluid Dynamics Analysis.

Hung-Chieh Wu, Fu-Lun Chen, Yuan-Ching Chiang, Yi-June Lo, Chun-Li Lin, Wei-Jen Chang, Haw-Ming Huang

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Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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7 authors.

Hung-Chieh WuSchool of Dentistry, Taipei Medical University, Taipei 11031, Taiwan.

Fu-Lun ChenDivision of Infectious Diseases, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan.

Yuan-Ching ChiangDepartment of Mechanical Engineering, Chinese Culture University, Taipei 11114, Taiwan.

Yi-June LoDivision of Periodontics, Department of Dentistry, Wan Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan.

Chun-Li LinDepartment of Biomedical Engineering, Medical Device Innovation and Translation Center, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.ORCID 0000-0002-5958-0949

Wei-Jen ChangSchool of Dentistry, Taipei Medical University, Taipei 11031, Taiwan.

Haw-Ming HuangSchool of Dentistry, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0003-4184-3744

Funding

Taipei Medical University-Wan Fang Hospital grant number 113TMU-WFH-16

6 · The paper itself

Abstract

Breath-actuated nebulizers used in aerosol therapy are vital to children and patients with disabilities and stand out for their ability to accurat ely deliver medication while minimizing waste. Their performance can be measured according to the mass output and droplet size. This study aimed to analyze how the baffle impact surface geometries affect the pressure and flow streamlines inside the nebulizer using computational fluid dynamics (CFD). Computer-aided design models of conical symmetric, conical asymmetric, and arc-shaped baffle designs were analyzed using CFD simulations, with the optimal spray output validated through the differences in mass. Conical baffles exhibited superior pressure distribution and output streamlines at 0.25 cm protrusion, suggesting that the nebulizer spray performance can be enhanced by using such a conical baffle impact surface. This result serves as a valuable reference for future research.

Indexed as

bafflebreath-actuated nebulizerCFD

Identifiers

PMID40722372

DOI10.3390/bioengineering12070680

PMCPMC12292640

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.