Evidence map›Paper›PMID 40722353›Full record

ReviewBrain sciences2025

Mental Health and Quality of Life in Patients with Untreated Unruptured Intracranial Aneurysms: A Systematic Review and Meta-Analysis of 417,152 Patients with Trial Sequential Analysis.

Plamen Penchev, Kiril Ivanov, Daniela Milanova-Ilieva, Lyubomir Gaydarski, Kiril Kostov, Nikola Boyadzhiev, Petar-Preslav Petrov, Patrice Mehandzhiev, Remzi Hyusein, Vladislav Velchev and 12 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Brain sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Plamen PenchevFaculty of Medicine, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.ORCID 0009-0000-9942-9357
Kiril IvanovFaculty of Medicine, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.
Daniela Milanova-IlievaDepartment of Pediatrics, St. George's University Hospital, 4000 Plovdiv, Bulgaria.
Lyubomir GaydarskiDepartment of Anatomy, Histology and Embryology, Medical University of Sofia, 1431 Sofia, Bulgaria.ORCID 0000-0003-4774-6507
Kiril KostovFaculty of Medicine, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.
Nikola BoyadzhievFaculty of Medicine, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.
Petar-Preslav PetrovDepartment of Anatomy, Histology and Embryology, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.
Patrice MehandzhievNeurosurgery Clinic, University Hospital "Pirogov", 1606 Sofia, Bulgaria.
Remzi HyuseinFaculty of Medicine, Medical University of Sofia, 1431 Sofia, Bulgaria.
Vladislav VelchevFaculty of Medicine, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.
Ilko IlyovFaculty of Medicine, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.
Valentin KuzmanovFaculty of Medicine, Medical University of Sofia, 1431 Sofia, Bulgaria.
Gergana DzhikovaFaculty of Medicine, Medical University of Sofia, 1431 Sofia, Bulgaria.
Desislava DobrevaFaculty of Medicine, Sofia University, 1504 Sofia, Bulgaria.
Liliana ToptchiyskaFaculty of Medicine, Sofia University, 1504 Sofia, Bulgaria.
Vasilena DimitrovaFaculty of Medicine, Medical University of Pleven, 5800 Pleven, Bulgaria.
Victoria PetrovaEye Clinic Den, 1000 Sofia, Bulgaria.
Svetoslav YorovDepartment of Anesthesiology, Klinik Hietzing, 1130 Wien, Austria.
Pavel StanchevClinic of Endocrinology and Metabolic Diseases, St. George's University Hospital, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.
Martin GyulbaharovDepartment of Anesthesiology, Asklepios Clinic, 23843 Bad Oldesloe, Germany.
Noor HusainDepartment of Pharmacology, Indira Gandhi Institute of Medical Sciences, Patna 800014, India.ORCID 0009-0002-6925-8926
Nikolai RamadanovCenter of Orthopaedics and Traumatology, Brandenburg Medical School, University Hospital Brandenburg, 14770 Brandenburg an der Havel, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anxietydepressionmental healthquality of life (QoL)unruptured intracranial aneurysm (UIA)untreated UIAs

Identifiers

PMID40722353
PMCPMC12293973

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.