Evidence map›Paper›PMID 40722296›Full record

ArticleBrain sciences2025

Relationship Between Nutritional Indexes and Clinical Outcomes in Stroke Patients Undergoing Mechanical Thrombectomy.

Özgür Zülfükar Ertuğrul, Fırat Karaaslan, Reşit Yılmaz, Mehmet Cudi Tuncer

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Article in Brain sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Özgür Zülfükar ErtuğrulGazi Yaşargil Training and Research Hospital, Department of Radiology, University of Health Sciences, Diyarbakır 21090, Turkey.
Fırat KaraaslanGazi Yaşargil Training and Research Hospital, Department of Neurology, University of Health Sciences, Diyarbakır 21090, Turkey.
Reşit YılmazGazi Yaşargil Training and Research Hospital, Department of Neurology, University of Health Sciences, Diyarbakır 21090, Turkey.
Mehmet Cudi TuncerFaculty of Medicine, Department of Anatomy, Dicle University, Diyarbakir 21090, Turkey.ORCID 0000-0001-7317-5467

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesNutritional status is increasingly acknowledged as a pivotal determinant of clinical course and recovery in patients with acute ischemic stroke (AIS). Malnutrition can compromise immune competence, delay neurological recovery, and exacerbate adverse outcomes, particularly in those undergoing intensive interventions such as mechanical thrombectomy (MT). To objectively assess nutritional status, indices such as the Prognostic Nutritional Index (PNI) and the Controlling Nutritional Status (CONUT) score have been utilized in various clinical populations. These indices incorporate routinely available laboratory parameters, reflecting both nutritional and inflammatory states. This study explores whether PNI and CONUT scores are associated with 90-day clinical outcomes in AIS patients treated with MT, aiming to evaluate their potential utility as prognostic biomarkers in acute stroke care.

methodsA total of 404 patients with AIS who underwent MT between 2023 and 2024 were retrospectively evaluated. Demographic, clinical, and laboratory data were collected, and nutritional status was assessed using PNI and CONUT scores. Clinical outcomes were stratified as favorable (modified Rankin Scale [mRS] 0-2) or unfavorable (mRS 3-6) at 90 days post-stroke.

resultsAmong the 404 patients included in the study, 50.5% had favorable and 49.5% had unfavorable clinical outcomes. Patients with favorable outcomes were younger (71 vs. 78 years,

conclusionsAmong the two nutritional indices evaluated, the CONUT score demonstrated significant prognostic value in predicting 90-day clinical outcomes after MT. In contrast, the PNI showed limited discriminatory power, highlighting the superiority of CONUT as a reliable biomarker in acute stroke care.

Indexed as

biomarkersnutritional statusprognosisstrokethrombectomy

Identifiers

PMID40722296
PMCPMC12294111

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