Evidence map›Paper›PMID 40722019›Full record

Trial reportBMC complementary medicine and therapies2025

Massage positively influences daytime brain activity and reduces arousal state in poor sleepers: a randomized controlled trial.

Ilias Ntoumas, Christina Karatzaferi, Fotini Boubougiatzi, Nefeli Manakou, Artemis Aslanidi, Christoforos D Giannaki, Fotini Papanikolaou, Efthimios Dardiotis, Eleftherios Lavdas, Giorgos K Sakkas

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC complementary medicine and therapies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06780072 (The Acute Effect of Manual Massage Therapy on Daytime Napping in Poor Sleepers), which is not on this map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06780072 nacompletednot on this map

The Acute Effect of Manual Massage Therapy on Daytime Napping in Poor Sleepers

TypeinterventionalSponsorUniversity of ThessalyRan2023 to 2024Enrolled15ConditionsSleep DeprivationArmsActivation Massage therapy, Relaxation Massage Therapy
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ilias NtoumasDepartment of Physical Education and Sport Science, School of Physical Education, Sports and Dietetics, University of Thessaly, 42100, Karies, Trikala, Greece.
Christina KaratzaferiDepartment of Physical Education and Sport Science, School of Physical Education, Sports and Dietetics, University of Thessaly, 42100, Karies, Trikala, Greece.
Fotini BoubougiatziDepartment of Physical Education and Sport Science, School of Physical Education, Sports and Dietetics, University of Thessaly, 42100, Karies, Trikala, Greece.
Nefeli ManakouDepartment of Physical Education and Sport Science, School of Physical Education, Sports and Dietetics, University of Thessaly, 42100, Karies, Trikala, Greece.
Artemis AslanidiDepartment of Physical Education and Sport Science, School of Physical Education, Sports and Dietetics, University of Thessaly, 42100, Karies, Trikala, Greece.
Christoforos D GiannakiDepartment of Life Sciences, School of Life and Health Sciences, University of Nicosia, 2417, Nicosia, Cyprus.
Fotini PapanikolaouDepartment of Physical Education and Sport Science, School of Physical Education, Sports and Dietetics, University of Thessaly, 42100, Karies, Trikala, Greece.
Efthimios DardiotisDepartment of Neurology, School of Medicine, University of Thessaly, 41110, Larisa, Greece.
Eleftherios LavdasDepartment of Biomedical Sciences, University of West Attica, 12243, Athens, Greece.
Giorgos K SakkasDepartment of Physical Education and Sport Science, School of Physical Education, Sports and Dietetics, University of Thessaly, 42100, Karies, Trikala, Greece. gsakkas@uth.gr.ORCID http://orcid.org/0000-0002-2462-995X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDaytime napping is used as a strategy to complement insufficient night-time sleep and improve daytime mental and physical performance. Massage can play a crucial role in promoting relaxation and wellness at various settings including the work place. The purpose of the present study was to investigate the effect of two different types of manual massage sessions on day-time napping in poor sleepers.

methodsThis was a randomized, single blind, placebo-controlled, three arm, interventional clinical trial. Fifteen participants (aged 21.6 ± 1.3 years) participated in three different conditions over one week apart: 1) 30-min Sports massage condition (ACT), 2) 30-min Relaxation massage condition (REL) and 3) control condition with no massage. Brain activity was monitored using a polysomnography EEG system, while vitals and relaxation/stress state were assessed by validated questionnaires and functional tests. The Pittsburgh Sleep Quality Index Score > 5 was used as cut off for distinguishing poor sleeper.

resultsResults showed significant differences between the three conditions, with muscle tone to be reduced by 7.2% after ACT session (p = 0.000) and relaxation scores to be increased by 23.4% after REL session (p = 0.008). In addition, Sleep Latency N1 was improved only after the REL session compared to other two conditions (p = 0.037).

conclusionsIn conclusion, massage can positively impact the quality and quantity of daytime napping and may serve as a complementary intervention to enhance mental well-being, reduce work related stress, improve performance and promote overall a healthier living.

trial registrationRetrospectively registered (registration date: 16/01/2025; trial registration number at ClinicalTrials.gov: NCT06780072).

Indexed as

ArousalBrainMassageSleepAdultElectroencephalographyFemaleHumansMalePolysomnographySingle-Blind MethodSleep QualityYoung AdultEEGHandgripRelaxation massageRSQSports massage

Identifiers

PMID40722019
PMCPMC12302761

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.