Evidence map›Paper›PMID 40722013›Full record

ArticleBMC ophthalmology2025

Repeatability, reproducibility, and agreement for three optical coherence tomography instruments.

Jiali Zhang, Muhan Zhong, Shuqi Fan, Xindan Chang, Xue Li, Hao Chen, Jinhua Bao, Yingying Huang

Abstract read
In one paragraph

Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiali Zhang *National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, Zhejiang, 325027, China.
Muhan Zhong *National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, Zhejiang, 325027, China.
Shuqi FanNational Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, Zhejiang, 325027, China.
Xindan ChangNational Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, Zhejiang, 325027, China.
Xue LiNational Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, Zhejiang, 325027, China.
Hao ChenNational Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, Zhejiang, 325027, China.
Jinhua BaoNational Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, Zhejiang, 325027, China. baojessie@mail.eye.ac.cn.
Yingying HuangNational Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, Zhejiang, 325027, China. huangyy@eye.ac.cn.

Funding

the Basic Scientific Research Project of Wenzhou Y2020343the Medical and Health Science and Technology Project of Zhejiang Provincial Health Commission of China 2022PY072
6 · The paper itself

Abstract

purposeTo explore the repeatability, reproducibility and agreement for three optical coherence tomography (OCT) in measuring retinal (RT) and choroidal thickness (ChT).

methodsSixty-eight eyes were included. The average RT and ChT were obtained with VG200I and Triton, while only the subfoveal RT (SFRT) and ChT (SFChT) were measured with RTVue. Operator 1 conducted two examinations to assess repeatability, and operator 2 conducted one for reproducibility. Built-in software was used to calculate RT-auto and ChT-auto, and custom-designed algorithms were used to calculate ChT-custom to assess interanalysis and intermachine agreements.

resultsThe intraclass correlation coefficients for the repeatability and reproducibility were larger than 0.760 and 0.940 with VG200I, 0.890 and 0.910 with Triton, and 0.960 and 0.975 with RTVue, respectively. The intermachine differences for SFRT and SFChT were - 8.82 ± 3.15 μm and - 41.89 ± 8.21 μm (VG200I vs. RTVue), -26.86 ± 3.15 μm and - 56.60 ± 7.81 μm (Triton vs. RTVue), and 18.04 ± 2.01 μm and 14.71 ± 3.02 μm (VG200I vs. Triton), respectively. The mean differences between VG200I and Triton in RT, ChT-auto and ChT-custom across the different regions ranged between 16.34 and 27.80 μm, 66.53 and 96.93 μm, and 4.48 and 18.32 μm, respectively. The mean differences between ChT-auto and ChT-custom across the different regions ranged between 29.06 and 43.71 μm for VG200I and - 48.73 and - 27.98 μm for Triton. The intermachine correlations were high, with ρ > 0.655 for all parameters.

conclusionThe three OCT devices all showed great repeatability and reproducibility, while the agreements between them were poor.

Indexed as

ChoroidRetinaTomography, Optical CoherenceAdultAgedFemaleHumansMaleMiddle AgedReproducibility of ResultsAgreementChoroidal thicknessOptical coherence tomographyRepeatabilityReproducibilityRetinal thickness

Identifiers

PMID40722013
PMCPMC12302902

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.