Evidence map›Paper›PMID 40721987›Full record

ArticleBMC anesthesiology2025

Assessment of nutritional indices for predicting clinical outcomes in critically ill elderly patients: a prospective cohort study.

Ugur Balaban, Nadir Yalcin, Esat Kivanc Kaya, Ebru Ortac Ersoy, Kutay Demirkan

Abstract read
In one paragraph

Article in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ugur BalabanDepartment of Clinical Pharmacy, Faculty of Pharmacy, Hacettepe University, Ankara, Türkiye. eczugurbalaban@gmail.com.ORCID http://orcid.org/0009-0002-7143-3260
Nadir YalcinDepartment of Clinical Pharmacy, Faculty of Pharmacy, Hacettepe University, Ankara, Türkiye.ORCID http://orcid.org/0000-0002-2280-8727
Esat Kivanc KayaDivision of Intensive Care Medicine, Department of Internal Medicine, Faculty of Medicine, Hacettepe University, Ankara, Türkiye.ORCID http://orcid.org/0000-0002-3449-0701
Ebru Ortac ErsoyDivision of Intensive Care Medicine, Department of Internal Medicine, Faculty of Medicine, Hacettepe University, Ankara, Türkiye.ORCID http://orcid.org/0000-0002-2534-1333
Kutay DemirkanDepartment of Clinical Pharmacy, Faculty of Pharmacy, Hacettepe University, Ankara, Türkiye.ORCID http://orcid.org/0000-0002-6427-5826

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalnutrition is a prevalent issue in critically ill elderly patients and is closely linked to poor clinical outcomes. This study aimed to assess the prognostic value of four nutritional indices-modified nutrition risk in the critically ill (mNUTRIC), Geriatric Nutritional Risk Index (GNRI), hemoglobin, albumin, lymphocyte, and platelet (HALP), and neutrophil-to-lymphocyte ratio (NLR)-in predicting intensive care unit (ICU) outcomes.

methodsThis prospective cohort study included elderly patients (aged ≥ 65 years) who were admitted to the medical ICU of a tertiary care university hospital. Nutritional indices (mNUTRIC, GNRI, HALP, and NLR) were evaluated for their prognostic value in predicting 28-day mortality, ICU mortality, and ICU length of stay (LOS) using multivariable regression and receiver operating characteristic (ROC) curve analyses.

resultsSeventy-three patients were included, with a median age (interquartile range) of 74 (10) years and 56.2% male. The mNUTRIC score was identified as an independent risk factor for 28-day mortality (OR = 2.505, 95%CI: 1.164-5.391, p = 0.019) and ICU mortality (OR = 2.736, 95%CI: 1.350-5.545, p = 0.005), with strong predictive performance (AUC: 0.864 and 0.858, respectively). It was also associated with prolonged ICU LOS (RR = 1.117, 95% CI: 1.033-1.207, p = 0.005). While GNRI exhibited good predictive performance (AUC: 0.811 and 0.799 for 28-day mortality and ICU mortality, respectively), it was not an independent factor. In contrast, HALP and NLR showed limited prognostic value for mortality.

conclusionsThe mNUTRIC score was identified as the strongest prognostic tool, with GNRI also demonstrating considerable predictive value for mortality outcomes, enhancing nutritional risk screening and clinical decision-making in elderly ICU patients.

Indexed as

Critical IllnessMalnutritionNutritional StatusNutrition AssessmentAgedAged, 80 and overCohort StudiesFemaleGeriatric AssessmentHospital MortalityHumansIntensive Care UnitsLength of StayMalePredictive Value of TestsPrognosisClinical outcomesIntensive care unitMalnutritionMortalityNutritional assessmentOlder patients

Identifiers

PMID40721987
PMCPMC12306058

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.