Evidence map›Paper›PMID 40721964›Full record

ArticleAnnals of surgical oncology2025

Laparoscopic Approach to a Rare Hypervascular Renal Vein Tumor: A Case of Anastomosing Hemangioma.

Giorgio D'Annibale, Matteo Aulicino, Cecilia Orsini, Carlo Abatini, Miriam Attalla El Halabieh, Valerio Gallotta, Andrea Rosati, Giovanni Tinelli, Francesco Santullo, Fabio Pacelli and 1 more

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Article in Annals of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Giorgio D'AnnibaleGeneral Surgery Department, Università Cattolica del Sacro Cuore, Rome, Italy.
Matteo AulicinoGeneral Surgery Department, Università Cattolica del Sacro Cuore, Rome, Italy. matteoaulicino95@gmail.com.
Cecilia OrsiniGeneral Surgery Department, Università Cattolica del Sacro Cuore, Rome, Italy.
Carlo AbatiniSurgical Unit of Peritoneum and Retroperitoneum Surgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Miriam Attalla El HalabiehSurgical Unit of Peritoneum and Retroperitoneum Surgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Valerio GallottaDepartment of Woman and Child Health and Public Health, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Andrea RosatiDepartment of Woman and Child Health and Public Health, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Giovanni TinelliUnit of Vascular Surgery, Department of Cardiovascular Sciences, Fondazione Policlinico Universitario Gemelli IRCCS-Università Cattolica del Sacro Cuore, Largo Agostino Gemelli, Rome, Italy.
Francesco SantulloSurgical Unit of Peritoneum and Retroperitoneum Surgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Fabio PacelliGeneral Surgery Department, Università Cattolica del Sacro Cuore, Rome, Italy.
Claudio LodoliSurgical Unit of Peritoneum and Retroperitoneum Surgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnastomosing hemangioma (AH) is a rare benign vascular neoplasm that histologically mimics angiosarcoma and has been reported in various sites, including the kidney, liver, adrenal gland, bladder, and retroperitoneum. When arising from the renal vein or its junction with the inferior vena cava, AH is exceptionally uncommon, with only a few cases described. Its hypervascular nature often leads imaging to suggest malignancy, making preoperative differentiation from angiosarcoma challenging. Surgical excision remains both diagnostic and curative, with laparoscopic resection feasible in selected cases and specialized centers.

methodsWe report the case of a 77-year-old man with an incidentally discovered retroperitoneal mass arising from the left renal vein and extending toward the inferior vena cava. Imaging revealed a well-enhancing hypervascular lesion suggestive of malignancy. After multidisciplinary evaluation, surgical excision without renal vein reconstruction was planned, supported by literature evidence on the safety of renal vein ligation without reconstruction. Postoperative Doppler ultrasound at 72 h confirmed adequate venous drainage via preserved tributary vessels. Follow-up at 6 months, including renal function tests and Doppler ultrasound, showed no renal dysfunction or morphologic abnormalities.

resultsThe accompanying video demonstrates step-by-step laparoscopic dissection and resection of the lesion, highlighting key anatomic landmarks, vascular control strategies, and techniques to minimize intraoperative bleeding. Histopathologic analysis revealed anastomosing capillary-sized vessels lined by bland endothelial cells, consistent with AH, with immunohistochemistry positive for CD34, SMA, and ERG.

conclusionsAH should be considered in the differential diagnosis of retroperitoneal vascular tumors. In cases involving major vascular structures, preoperative biopsy is often unfeasible, and surgical excision becomes necessary for definitive diagnosis and treatment. Laparoscopic resection can be performed safely in high-volume centers, offering the benefits of minimally invasive surgery along with excellent oncologic and functional outcomes.

Indexed as

HemangiomaLaparoscopyRenal VeinsVascular NeoplasmsAgedHumansMalePrognosis

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