Evidence map›Paper›PMID 40721879›Full record

SynthesisProstate cancer and prostatic diseases2026

Machine learning-based MRI imaging for prostate cancer diagnosis: systematic review and meta-analysis.

Yusheng Zhao, Lei Zhang, Subo Zhang, Jiajing Li, Kaimin Shi, Di Yao, Qiuzi Li, Tao Zhang, Lei Xu, Lei Geng and 2 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Prostate cancer and prostatic diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yusheng Zhao *Department of Medical Imaging, The Second People's Hospital of Lianyungang, Lianyungang city, China.
Lei Zhang *Department of Information System, Lianyungang 149 Hospital, Lianyungang city, China.
Subo ZhangDepartment of Medical Imaging, The Second People's Hospital of Lianyungang, Lianyungang city, China.
Jiajing LiDepartment of Medical Imaging, The Second People's Hospital of Lianyungang, Lianyungang city, China.
Kaimin ShiDepartment of Technology, , Jiangsu Jerry Technology Co. Ltd., Lianyungang city, China.
Di YaoDepartment of Technology, , CGN (Jiangsu) New Energy Resources Co. Ltd., Lianyungang city, China.
Qiuzi LiDepartment of Integrated Management, Lianyungang Haizhou Bay Marine Fisheries Development Institute, Lianyungang city, China.
Tao ZhangDepartment of Medical Imaging, The Second People's Hospital of Lianyungang, Lianyungang city, China.
Lei XuDepartment of Medical Imaging, The Second People's Hospital of Lianyungang, Lianyungang city, China.
Lei GengDepartment of Medical Imaging, The Second People's Hospital of Lianyungang, Lianyungang city, China.
Yi SunDepartment of Medical Imaging, The Second People's Hospital of Lianyungang, Lianyungang city, China. sunyi2sdf@outlook.com.
Jinxin WanDepartment of Medical Imaging, The Second People's Hospital of Lianyungang, Lianyungang city, China. jjjjiiiinnnn_3054@163.com.ORCID http://orcid.org/0009-0004-0407-5736

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to evaluate the diagnostic value of machine learning-based MRI imaging in differentiating benign and malignant prostate cancer and detecting clinically significant prostate cancer (csPCa, defined as Gleason score ≥7) using systematic review and meta-analysis methods.

methodsElectronic databases (PubMed, Web of Science, Cochrane Library, and Embase) were systematically searched for predictive studies using machine learning-based MRI imaging for prostate cancer diagnosis. Sensitivity, specificity, and area under the curve (AUC) were used to assess the diagnostic accuracy of machine learning-based MRI imaging for both benign/malignant prostate cancer and csPCa.

resultsA total of 12 studies met the inclusion criteria, with 3474 patients included in the meta-analysis. Machine learning-based MRI imaging demonstrated good diagnostic value for both benign/malignant prostate cancer and csPCa. The pooled sensitivity and specificity for diagnosing benign/malignant prostate cancer were 0.92 (95% CI: 0.83-0.97) and 0.90 (95% CI: 0.68-0.97), respectively, with a combined AUC of 0.96 (95% CI: 0.94-0.98). For csPCa diagnosis, the pooled sensitivity and specificity were 0.83 (95% CI: 0.77-0.87) and 0.73 (95% CI: 0.65-0.81), respectively, with a combined AUC of 0.86 (95% CI: 0.83-0.89).

conclusionMachine learning-based MRI imaging shows good diagnostic accuracy for both benign/malignant prostate cancer and csPCa. Further in-depth studies are needed to validate these findings.

Indexed as

Machine LearningMagnetic Resonance ImagingProstatic NeoplasmsHumansMaleNeoplasm GradingSensitivity and Specificity

Identifiers

PMID40721879
PMCPMC12909110

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.