Evidence map›Paper›PMID 40721864›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Evaluating recruitment, retention, and adherence patterns in the GET FIT fall prevention exercise trial in older, postmenopausal cancer survivors.

Jessica Sitemba, Mary Crisafio, Fuzhong Li, Elizabeth Eckstrom, Kerri M Winters-Stone

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01635413 (Group Exercise Training for Functional Improvement After Treatment), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01635413 nacompletednot on this map

Group Exercise Training for Functional Improvement After Treatment (The GET FIT Trial)

TypeinterventionalSponsorOHSU Knight Cancer InstituteRan2012 to 2016Enrolled444ConditionsMalignant Neoplasm, PostmenopausalArmsExercise Intervention, Questionnaire Administration
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Jessica SitembaDivision of Oncological Sciences, Oregon Health & Science University, 3455 SW US Veteran's Hospital Rd, Portland, OR, 97239, USA.
Mary CrisafioDivision of Oncological Sciences, Oregon Health & Science University, 3455 SW US Veteran's Hospital Rd, Portland, OR, 97239, USA.
Fuzhong LiOregon Research Institute, Springfield, OR, USA.
Elizabeth EckstromDivision of General Internal Medicine & Geriatrics, Oregon Health & Science University, Portland, OR, USA.
Kerri M Winters-StoneDivision of Oncological Sciences, Oregon Health & Science University, 3455 SW US Veteran's Hospital Rd, Portland, OR, 97239, USA. wintersk@ohsu.edu.

Funding

Preventing falls after cancer: Tai chi vs. strength trainingR01CA163474 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI WINTERS-STONE, KERRI M · 2012 to 2016
$3.0M
CCR NIH HHS R01CA163474
6 · The paper itself

Abstract

purposeThe GET FIT trial tested fall prevention exercise approaches in older (50-75 years) post-chemotherapy, postmenopausal cancer survivors. We describe recruitment, retention, and adherence patterns from GET FIT to inform future trials.

methodsParticipants were recruited through multiple strategies (e.g., cancer and research registries, clinician referral, outreach, electronic health record (EHR) screening) and were randomized to one of three supervised, facility-based, group exercise programs (strength training, tai ji quan, or stretching control) for 6 months and then were followed for 6 months after supervised training stopped. We compared effectiveness of accrual across recruitment strategies, examined characteristics of women who completed the interventions to those who withdrew, and women with good (≥ 50%) versus poor (< 50%) adherence to training.

resultsOf 1490 interested women, 442 women were eligible, randomized, and received the assigned intervention (30% accrual rate). Accrual was similar across recruitment strategies, except for EHR screening which yielded no accruals. Retention over 12 months was 87% with most dropouts occurring within the first month. There were no differences in baseline characteristics between women who did or did not drop out. Poor adherers (n = 60) had higher baseline BMI, comorbidities, pain, disability, and lower physical functioning (p < 0.05) compared to more adherent women (n = 377).

conclusionsA variety of recruitment strategies appear to be effective for enrolling older, postmenopausal cancer survivors into a facility-based exercise trial, except for directly approaching women identified through the EHR. Women with poorer health were at risk for study drop-out and poor adherence to exercise. IMPLICATIONS FOR CANCER SURVIVORS: Women with poorer initial health may need additional retention strategies to help them stick with supervised, facility-based, group exercise.

trial registrationClinicaltrials.gov: NCT01635413.

Indexed as

Accidental FallsCancer SurvivorsExercise TherapyPatient CompliancePatient SelectionAgedFemaleHumansMiddle AgedPostmenopauseResistance TrainingTai JiCancer survivorshipExercise trainingFall preventionFeasibilityOlder adult

Identifiers

PMID40721864

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.