Evidence map›Paper›PMID 40721810›Full record

ArticleJournal of orthopaedic surgery and research2025

Efficacy of manual therapy for cervical vertigo: a randomized controlled trial protocol.

Chao Lu, Jie Chen, Feng Gao, Donggang Pan, Xian Wang, Shinian Zhang

Abstract readClinical Trial Protocol
In one paragraph

Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chao Lu *Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu Province, China.
Jie Chen *Department of Rehabilitation Medicine, Zhenjiang Hospital of Traditional Chinese and Western Medicine, Zhenjiang, Jiangsu Province, 212002, China.
Feng GaoAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu Province, China.
Donggang PanZhenjiang First People's Hospital, Zhenjiang, Jiangsu, 212002, China.
Xian WangZhenjiang First People's Hospital, Zhenjiang, Jiangsu, 212002, China.
Shinian ZhangAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu Province, China. zhangshinian@sina.com.

Funding

Zhenjiang Science and Technology Bureau Project SH2023096
6 · The paper itself

Abstract

backgroundCervical vertigo (CV) is highly prevalent clinically, yet effective treatments are limited. Manual therapy, an important alternative, shows potential in the treatment of patients with CV. Unfortunately, the quality of current relevant research evidence is poor, and most manual therapies only focus on the local cervical spine. There are few studies on whole-spine synergistic manual therapy. Therefore, we aimed to conduct a randomized controlled trial (RCT) to explore the short-term efficacy of synergistic manual therapy for patients with. CV.

methodsThe clinical study is RCT. A total of 138 patients will be randomly assigned to the synergistic manual therapy (SM) group, cervical manual therapy (CM) group, or waiting list (WL) group in a 1:1:1 ratio for 2 weeks with a 3-month follow-up. The primary outcome will be the mean change of vertigo intensity measured by the Dizziness Handicap Inventory (DHI). The secondary outcomes will include the vertebrobasilar artery blood flow velocity, the Essex-Symonds Cervical Vertebral Index Scale (ESCV) score, 36-item Short-Form Health Survey (SF-36) score, and adverse events (AEs). DISCUSSION: This randomized trial will be the first rigorous study designed to assess the short-term efficacy of SM therapy in comparison with local CM therapy or no treatment among patients with CV. The finding of this study will provide an objective clinical basis for the use of SM therapy for patients with CV in the future.

trial registrationInternational Traditional Medicine Clinical Trials, ITMCTR2025000184. Registered on 25 January 2025.

Indexed as

Cervical VertebraeManipulation, SpinalMusculoskeletal ManipulationsVertigoAdultFemaleHumansMaleMiddle AgedRandomized Controlled Trials as TopicTreatment OutcomeCervical vertigoManual therapyPlaceboRandomized controlled trialShort-term efficacy

Identifiers

PMID40721810
PMCPMC12305973

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.