Evidence map›Paper›PMID 40721796›Full record

SynthesisBMC surgery2025

Prevalence and surgical outcomes of pediatric intussusception in ethiopia: a systematic review and meta-analysis.

Yohannis Derbew Molla, Desyibelew Chanie Mekonnen, Hirut Tesfahun Alemu

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yohannis Derbew MollaDepartment of Surgery, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia. yderbew73@gmail.com.
Desyibelew Chanie MekonnenDepartment of Surgery, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Hirut Tesfahun AlemuCollege of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntussusception is the leading cause of pediatric abdominal emergencies worldwide, requiring timely diagnosis and intervention to prevent life-threatening complications. In low-resource settings such as Ethiopia, delayed presentation and limited access to non-surgical management often necessitate surgical intervention. However, comprehensive data on surgical outcomes and complications remain scarce. The aim of this study is to evaluate the epidemiology, clinical presentation, surgical management, and postoperative outcomes of pediatric intussusception in Ethiopia.

methodsA systematic review was conducted following PRISMA guidelines. Relevant studies were retrieved from PubMed, Scopus, Web of Science, and Google Scholar. Data were extracted on patient demographics, clinical presentation, diagnostic. methods, surgical procedures, complications, and mortality. Quality assessment was performed using the Newcastle-Ottawa Scale. Meta-analysis was conducted using a random-effects model with heterogeneity assessed by I² statistics. Publication bias was evaluated using Egger's test.

resultsSeven studies with a total of 672 patients were included. The mean age of affected children was 12 months (95% CI: 11.35, 12.67), with a male predominance (66%). Delayed presentation was common, with a mean time of 3.1 days from symptom onset. The classic triad of symptoms-abdominal pain, bloody stools, and a palpable mass-was present in 52% of cases (I² = 96.24%). Ultrasound was the most common diagnostic tool (74%). The most frequent surgical intervention was manual reduction (62%), followed by bowel resection with anastomosis (35%) and stoma creation. The overall complication rate was 26%, with surgical site infections (15%) being the most common. The pooled mortality rate was 9% (95% CI: 5%, 13%), significantly higher than in high-income countries. Egger's test (p = 0.03) suggested potential publication bias.

conclusionThis study found that surgically managed pediatric intussusception in Ethiopia had a high morbidity and mortality rate. These outcomes may reflect delays in presentation, and advanced disease at intervention. The development and implementation of context-specific clinical guidelines could help optimize care and improve survival rates. In addition, further research is needed to evaluate the impact of non-surgical reduction techniques.

Indexed as

IntussusceptionChildChild, PreschoolEthiopiaHumansInfantPostoperative ComplicationsPrevalenceTreatment OutcomeEthiopiaIntussusceptionMeta-AnalysisPediatric surgerySurgical outcomesSystematic review

Identifiers

PMID40721796
PMCPMC12302767

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.