Evidence map›Paper›PMID 40721760›Full record

ArticleBMC oral health2025

Factors influencing recurrence after in-hospital treatment of odontogenic-related oromaxillofacial infections: a single-centre experience.

Andreas Sakkas, Majeed Rana, Mario Scheurer, Robin Kasper, Marcel Ebeling, Frank Wilde, Alisa Schramm, Jasmin Engelbrecht

Abstract read
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andreas SakkasDepartment of Oral and Maxillofacial Surgery, University Hospital Ulm, Albert-Einstein-Allee 11, 89081, Ulm, Germany. andreas.sakkas@uni-ulm.de.
Majeed RanaDepartment of Oral and Maxillofacial Surgery, University Hospital Ulm, Albert-Einstein-Allee 11, 89081, Ulm, Germany.
Mario ScheurerDepartment of Oral and Maxillofacial Surgery, University Hospital Ulm, Albert-Einstein-Allee 11, 89081, Ulm, Germany.
Robin KasperDepartment of Oral and Plastic Maxillofacial Surgery, Military Hospital Ulm, Ulm, Germany.
Marcel EbelingDepartment of Oral and Maxillofacial Surgery, University Hospital Ulm, Albert-Einstein-Allee 11, 89081, Ulm, Germany.
Frank WildeDepartment of Oral and Maxillofacial Surgery, University Hospital Ulm, Albert-Einstein-Allee 11, 89081, Ulm, Germany.
Alisa SchrammDepartment of Otolaryngology, Head and Neck Surgery, Military Hospital Ulm, Ulm, Germany.
Jasmin EngelbrechtDepartment of Oral and Maxillofacial Surgery, University Hospital Ulm, Albert-Einstein-Allee 11, 89081, Ulm, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEvidence regarding specific factors influencing recurrence after treatment of oromaxillofacial infections is limited. This study aimed to evaluate the incidence and identify predictors of recurrence following in-hospital treatment. A secondary aim was to analyze associations between patient- and procedure-specific variables, treatment outcomes, and hospital length of stay (LOS), and to identify high-risk patients.

methodsIn this retrospective, single-center study, patients with odontogenic-related oromaxillofacial infections treated surgically or conservatively over a 4-year period were included. Demographic, clinical, radiological, and treatment data were analyzed. Multivariable analyses were performed to identify predictors of recurrence and LOS.

resultsA total of 939 patients (mean age 44.66 ± 22.95 years) met the inclusion criteria. The recurrence rate was 5.01%, and the mean LOS was 3.55 ± 2.47 days. Increased age and BMI, mandibular infections, infections post-extraction or post-augmentation, clinical symptoms at admission (restricted mouth opening, dysphagia, non-palpable mandibular margin), elevated inflammatory markers (CRP, leukocytes, neutrophils, procalcitonin), and cervical drainage were significantly associated with higher recurrence risk and increased LOS (p < 0.05). A postoperative ICU stay increased the recurrence risk 9.13-fold.

conclusionsWithin the limitations of this study, the results suggest that older age, higher BMI, mandibular involvement, post-extraction or post-augmentation infections, specific clinical symptoms at admission (restricted mouth opening, dysphagia, non-palpable mandibular margin), elevated inflammatory markers, cervical drainage approaches, and stay in ICU are associated with both a higher risk of infection recurrence and increased hospital stay. Multiple bacterial strains and no continuous antibiotic therapy after discharge also indicated a higher risk of recurrence, while surgery under intubation anesthesia was linked to an increased length of stay only. These factors should be considered early in treatment planning to optimize outcomes. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

InfectionsJaw DiseasesMouth DiseasesAdultAgedFemaleHospitalizationHumansLength of StayMaleMiddle AgedRecurrenceRetrospective StudiesRisk FactorsYoung AdultIn-hospital treatmentOdontogenic abscessOromaxillofacial infectionRecurrence

Identifiers

PMID40721760
PMCPMC12305926

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.