Evidence map›Paper›PMID 40721681›Full record

ReviewHerzschrittmachertherapie & Elektrophysiologie2025

Sports or no sports? How to manage the young arrhythmia patient.

Ilger Ertugrul, Nico A Blom, European Reference Network for Rare Diseases of the Heart (ERN GUARDHEART)

Abstract readReview
In one paragraph

Review in Herzschrittmachertherapie & Elektrophysiologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ilger ErtugrulPediatric Cardiology, Department of Pediatrics, Ihsan Dogramaci Children's Hospital, Hacettepe University, Ankara, Turkey.
Nico A BlomDepartment of Pediatric Cardiology, Amsterdam University Medical Center, Amsterdam, The Netherlands. n.a.blom@lumc.nl.
European Reference Network for Rare Diseases of the Heart (ERN GUARDHEART)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInherited arrhythmia syndromes and cardiomyopathies are among the most concerning causes of sudden cardiac death in young individuals, particularly in the context of physical activity. Historically, sports participation in these patients has been broadly restricted due to safety concerns. However, emerging data and updated guidelines suggest that a more individualized approach may be both appropriate and safe.

objectivesThe aim of this study was to review current evidence and evolving recommendations regarding sports participation in young individuals with inherited cardiac diseases. MATERIALS AND

methodsThis review synthesizes recent studies, expert consensus statements, and current international guidelines (ESC, AHA/ACC).

resultsRecent data indicate that, in selected patients with inherited arrhythmia syndromes and cardiomyopathies who have undergone thorough evaluation and counseling, participation in sports-under appropriate precautions-may be safe and well tolerated. Emerging studies report low incidence of adverse events in appropriately managed athletes. Guidelines have shifted away from blanket restrictions and towards shared decision-making, especially in asymptomatic individuals or those with controlled disease. Key factors include genotype-phenotype correlation, history of arrhythmic events, treatment adherence, and patient/family understanding of risks.

conclusionIn contrast to traditional dogma, a growing body of evidence supports less restrictive, patient-centered management for young individuals with inherited cardiac conditions. With proper evaluation, risk stratification, and informed decision-making, sports participation and leisure time activities may be possible-and even beneficial-for many of these patients.

Indexed as

Arrhythmias, CardiacDeath, Sudden, CardiacSportsAdolescentAdultCardiomyopathiesChildHumansYoung AdultInherited cardiac diseasesPediatricsShared decision-makingSports participationSudden cardiac death

Identifiers

PMID40721681
PMCPMC12457478

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.