Evidence map›Paper›PMID 40721619›Full record

ArticleScientific reports2025

Development and validation of a visual nomogram for predicting clinically significant prostate cancer in negative mpMRI using

Wei Hu, ShiKuan Guo, XiangLiang Meng, FuLi Wang, ShuaiJun Ma, Chao Zhang, JingYi Wang, Lei Yuan, LongLong Zhang, YuMing Jing and 11 more

Abstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. The value of [Quantitative imaging in medicine and surgery · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Wei HuDepartment of Urology, Xijing Hospital, Fourth Military Medical University, No.127, Changle West Road, Xi'an, 710032, Shaanxi, China.
ShiKuan GuoDepartment of Urology, No.988th Hospital of Joint Logistic Support Force of PLA, Zhengzhou, Henan, China.
XiangLiang MengDepartment of Urology, Xijing Hospital, Fourth Military Medical University, No.127, Changle West Road, Xi'an, 710032, Shaanxi, China.
FuLi WangDepartment of Urology, Xijing Hospital, Fourth Military Medical University, No.127, Changle West Road, Xi'an, 710032, Shaanxi, China.
ShuaiJun MaDepartment of Urology, Xijing Hospital, Fourth Military Medical University, No.127, Changle West Road, Xi'an, 710032, Shaanxi, China.
Chao ZhangDepartment of Urology, Xijing Hospital, Fourth Military Medical University, No.127, Changle West Road, Xi'an, 710032, Shaanxi, China.
JingYi WangDepartment of Nuclear Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Lei YuanRadiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
LongLong ZhangDepartment of Urology, Xijing Hospital, Fourth Military Medical University, No.127, Changle West Road, Xi'an, 710032, Shaanxi, China.
YuMing JingDepartment of Urology, Xijing Hospital, Fourth Military Medical University, No.127, Changle West Road, Xi'an, 710032, Shaanxi, China.
Jian ChenDepartment of Urology, Northwest University First Hospital, Xi'an, China.
HaoZhong HouDepartment of Urology, Xijing Hospital, Fourth Military Medical University, No.127, Changle West Road, Xi'an, 710032, Shaanxi, China.
Yang WangRadiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
KeYing ZhangDepartment of Urology, Xijing Hospital, Fourth Military Medical University, No.127, Changle West Road, Xi'an, 710032, Shaanxi, China.
Yu LiDepartment of Urology, Xijing Hospital, Fourth Military Medical University, No.127, Changle West Road, Xi'an, 710032, Shaanxi, China.
Fei KangDepartment of Nuclear Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
DongHui HanDepartment of Urology, Xijing Hospital, Fourth Military Medical University, No.127, Changle West Road, Xi'an, 710032, Shaanxi, China.
HongQian GuoDepartment of Urology, Institute of Urology, Nanjing Drum Tower Hospital, Affiliated Hospital of Nanjing University Medical School, Nanjing University, Nanjing, China.
JingLiang ZhangDepartment of Urology, Xijing Hospital, Fourth Military Medical University, No.127, Changle West Road, Xi'an, 710032, Shaanxi, China.
Jing RenRadiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
WeiJun QinDepartment of Urology, Xijing Hospital, Fourth Military Medical University, No.127, Changle West Road, Xi'an, 710032, Shaanxi, China. qinwj_fmmu@163.com.

Funding

Medical Scientific Research Projects of Dalian 20Z12019National Natural Science Foundation of China 82302244
6 · The paper itself

Abstract

Multi-parametric magnetic resonance imaging (mpMRI) is a valuable medical technology for detecting clinically significant prostate cancer (csPCa). The diagnostic accuracy of mpMRI for csPCa in negative mpMRI (PI-RADS 1-2) remains suboptimal, underscoring the need for improvements for csPCa. This study aimed to build a visual predictive nomogram for early detection of csPCa in negative mpMRI. We retrospectively reviewed 303 men from our institution who simultaneously underwent

Indexed as

Multiparametric Magnetic Resonance ImagingNomogramsPositron Emission Tomography Computed TomographyProstatic NeoplasmsAgedEdetic AcidGallium IsotopesGallium RadioisotopesHumansMaleMiddle AgedOligopeptidesProstate-Specific AntigenRetrospective StudiesEdetic Acidgallium 68 PSMA-11Gallium IsotopesGallium RadioisotopesOligopeptidesProstate-Specific Antigen68Ga-PSMA PET/CTDiagnosisMpMRINomogramProstate cancer

Identifiers

PMID40721619
PMCPMC12304145

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.