Effects of Scutellaria baicalensis, Folium Artemisiae argyi, and Galla Chinensis on the protein expression and resistance genes of Exiguobacterium sp. in response to gentamicin.

Xiaohui Wang, Chang Luo, Hua Zhang, Jian Huang, Lei Sun, Tao Ma

Abstract read

In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Xiaohui WangCollege of Environmental and Energy Engineering, Anhui Jianzhu University, Hefei, 230061, China.

Chang LuoCollege of Environmental and Energy Engineering, Anhui Jianzhu University, Hefei, 230061, China.

Hua ZhangCollege of Environmental and Energy Engineering, Anhui Jianzhu University, Hefei, 230061, China. zhanghua@ahjzu.edu.cn.

Jian HuangCollege of Environmental and Energy Engineering, Anhui Jianzhu University, Hefei, 230061, China.

Lei SunCollege of Environmental and Energy Engineering, Anhui Jianzhu University, Hefei, 230061, China.

Tao MaCollege of Environmental and Energy Engineering, Anhui Jianzhu University, Hefei, 230061, China.

Funding

Anhui Provincial Key Research and Development Project 2023t07010002Cultivating academic (or disciplinary) leaders DTR2023029Natural Sci-ence Research Project of Colleges of Anhui Province 2022AH050236Natural Science Research Project of Colleges of Anhui Province KJ2021A0619the National Natural Science Foundation of China 52300022the Natural Science Foundation of Hefei 202310

6 · The paper itself

Abstract

Currently, the issue of antibiotic resistance genes as emerging pollutants in the environment has attracted significant attention in the field of environmental pollution research. Moreover, plant-derived compounds has become a research hotspot due to its high efficiency and low toxicity in reversing microbial intracellular antibiotic resistance genes. However, there is little research on the impact of specific plant extracts on proteins and antibiotic resistance genes during the process of reversing antibiotic resistance genes. In this study, the phosphorus removal performance test, combined with protein Raman spectroscopy analysis and antibiotic resistance gene abundance detection methods, was employed to investigate the effects of Scutellaria baicalensis, Folium Artemisiae argyi, and Galla Chinensis on the phosphorus removal rate, intracellular protein binding sites, and antibiotic resistance gene abundance of Exiguobacterium sp. after exposure to gentamicin. The Raman spectroscopy test results revealed a shift in the protein peaks of Exiguobacterium sp., transitioning from the stable C = C = C = C, C = C, C = C = C structures found in drug-resistant Exiguobacterium sp. to unsaturated bonds of C, CH

Indexed as

Anti-Bacterial AgentsBacterial ProteinsDrug Resistance, BacterialGene Expression Regulation, BacterialGentamicinsPlant ExtractsScutellaria baicalensisDrugs, Chinese HerbalTanninsAnti-Bacterial AgentsBacterial ProteinsDrugs, Chinese HerbalGalla chinensisGentamicinsPlant ExtractsTanninsAntimicrobial resistance reversalPolyphosphate bacteriaProteinsResistance genes

Identifiers

PMID40721471

DOI10.1016/J.JEP.2021.114247

PMCPMC12304318

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.