Evidence map›Paper›PMID 40721423›Full record

ArticleScientific reports2025

Outcomes of modified arthrocentesis using concentric needle and cannula technique with sequential viscosupplementation and orthobiologics in both TMJ compartments.

Eduardo Januzzi, Patrícia Pauletto, Thays Crossara Abrahão Cunha, Graziella Silva, Murilo Kazuo Iwassake, Miguel de Pedro, Juan Fernandez, Alexsander Ribeiro Pedrosa, Beatriz Dulcinéia Mendes de Souza, Adriana Soares Bicalho Duarte and 6 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Eduardo JanuzziOrofacial Pain Center of the Mater Dei Hospital, Postgraduate Program in Orofacial Pain and Temporomandibular Disorders, Neon Cursos, Belo Horizonte, Minas Gerais, Brazil.ORCID http://orcid.org/0000-0001-6727-8099
Patrícia PaulettoUniversidad de Las Américas, Quito, Ecuador. patricia.pauletto.p@gmail.com.ORCID http://orcid.org/0000-0002-1762-7059
Thays Crossara Abrahão CunhaFederal University of Uberlândia, Uberlândia, Minas Gerais, Brazil.ORCID https://orcid.org/0000-0003-2361-1157
Graziella SilvaEuropean Centre of Dentistry Speciality, Lisbon, Portugal.ORCID https://orcid.org/0000-0002-3475-4906
Murilo Kazuo IwassakeFederal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.ORCID https://orcid.org/0000-0003-1422-2141
Miguel de PedroOrofacial Pain, Oral Pathology and Dental Sleep Medicine Research Group, Department of Postgraduate Clinical Dentistry, European University of Madrid, Madrid, Spain.ORCID https://orcid.org/0000-0002-7873-8000
Juan FernandezServiço de Cirurgia Oral y Maxilofacial Hospital Universitário Sanitas La Zarzuela, Madrid, Spain.ORCID https://orcid.org/0009-0007-1124-2311
Alexsander Ribeiro PedrosaOrofacial Pain Center of the Mater Dei Hospital, Belo Horizonte, Minas Gerais, Brazil.ORCID https://orcid.org/0009-0009-9378-9648
Beatriz Dulcinéia Mendes de SouzaFederal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.ORCID https://orcid.org/0000-0003-4277-287X
Adriana Soares Bicalho DuarteFaculty of Sete Lagoas, Sete Lagoas, Minas Gerais, Brazil.ORCID https://orcid.org/0000-0002-7717-782X
Marcella Rezende Serpa ZaniniFaculty of Sete Lagoas, Sete Lagoas, Minas Gerais, Brazil.ORCID https://orcid.org/0009-0008-2627-1577
Isabela HübnerOrofacial Pain Center of the Mater Dei Hospital, Postgraduate Program in Orofacial Pain and Temporomandibular Disorders, Neon Cursos, Belo Horizonte, Minas Gerais, Brazil.ORCID https://orcid.org/0009-0001-6255-9585
Susana PerdigotoResearch Group, European University of Madrid, Madrid, Spain.ORCID https://orcid.org/0009-0001-0885-492X
Pedro Gonçalves de OliveiraInstituto de Ortopedia e Traumatologia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-9853-0031
Antônio Luís Neto CustódioBiological Sciences Institute of the Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.ORCID https://orcid.org/0000-0003-2211-9195
Mauricio Augusto Aquino de CastroDepartment of Dental Clinics, Oral Pathology and Oral Surgery of the Faculty of Dentistry of the Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.ORCID https://orcid.org/0000-0001-6013-9344

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Minimally invasive therapeutic procedures have been applied for the management of degenerative joint disease in the temporomandibular joint (TMJ). This study describes a modified technique of arthrocentesis with concentric needle and cannula in the TMJ associated with viscosupplementation and/or orthobiologics. Its effects were evaluated based on clinical outcomes related to pain, mouth opening, and joint sound, along with longitudinal tomographic evaluation based on the Wilkes classification. A prospective study was conducted with 22 patients (44 TMJs) undergoing arthrocentesis complemented by ultrasonography. The technique allowed effective lavage followed by infiltration into both the upper and lower compartments, using therapeutic agents selected based on the stage of articular temporomandibular disorder (TMD) according to the Wilkes classification. Clinical and tomographic assessments were performed before and after treatment, with follow-up ranging from 12 to 14 months. Significant improvements in pain outcomes (p < 0.001) and mouth opening amplitude (p < 0.001) were observed in all patients. There were no significant changes in joint sound post-treatment. The Wilkes classification revealed a reduction in degenerative stages in both the right (p = 0.003) and the left (p = 0.007) TMJs. The modified arthrocentesis technique combined with viscosupplementation and/or orthobiologics (platelet-rich fibrin) has been shown to be effective in reducing pain and improving TMJ function, suggesting a minimally invasive and safe approach for managing advanced articular TMDs. Future studies are recommended to confirm its applicability in different populations and in individuals with vary stages of TMD.

Indexed as

ArthrocentesisTemporomandibular JointTemporomandibular Joint DisordersViscosupplementationAdultAgedCannulaFemaleHumansMaleMiddle AgedNeedlesProspective StudiesTreatment OutcomeUltrasonographyArthrocentesisTemporomandibular disorderTemporomandibular joint

Identifiers

PMID40721423
PMCPMC12304328

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.