Evidence map›Paper›PMID 40721319›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2025

Ciliary ARL13B Is Essential for Vision and Morphogenesis of Cone Outer Segments.

Alexis Crockett, Sierra Kuzak, Thamaraiselvi Saravanan, Tongju Guan, Tamara Caspary, Hunter Aliff, George Holmes, Faezeh Moakedi, Visvanathan Ramamurthy

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexis CrockettDepartments of Neuroscience, West Virginia University, School of Medicine, Morgantown, West Virginia 26506.
Sierra KuzakBiochemistry and Molecular Medicine, West Virginia University, School of Medicine, Morgantown, West Virginia 26506.
Thamaraiselvi SaravananBiochemistry and Molecular Medicine, West Virginia University, School of Medicine, Morgantown, West Virginia 26506.
Tongju GuanBiochemistry and Molecular Medicine, West Virginia University, School of Medicine, Morgantown, West Virginia 26506.
Tamara CasparyDepartment of Human Genetics, Emory University School of Medicine, Atlanta, Georgia 30322.
Hunter AliffBiochemistry and Molecular Medicine, West Virginia University, School of Medicine, Morgantown, West Virginia 26506.
George HolmesBiochemistry and Molecular Medicine, West Virginia University, School of Medicine, Morgantown, West Virginia 26506.
Faezeh MoakediBiochemistry and Molecular Medicine, West Virginia University, School of Medicine, Morgantown, West Virginia 26506.
Visvanathan RamamurthyBiochemistry and Molecular Medicine, West Virginia University, School of Medicine, Morgantown, West Virginia 26506 ramamurthyv@hsc.wvu.edu.

Funding

VS-CoBRE Administrative CoreP20GM144230 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Visvanathan Ramamurthy · 2022 to 2026
$13.9M
Importance of Small GTPases in Photoreceptor FunctionR01EY028035 · NEI · WEST VIRGINIA UNIVERSITY · PI Visvanathan Ramamurthy · 2017 to 2026
$3.2M
Role of AIPL1 in Inherited Retinal Degenerative DiseaseR01EY017035 · NEI · WEST VIRGINIA UNIVERSITY · PI RAMAMURTHY, VISVANATHAN · 2007 to 2015
$3.1M
Genetic Dissection of Signaling and CiliaR35GM148416 · NIGMS · EMORY UNIVERSITY · PI TAMARA J. CASPARY · 2023 to 2026
$2.1M
Biosynthesis and trafficking of phosphodiesterase in the retinal photoreceptorsR01EY031346 · NEI · WEST VIRGINIA UNIVERSITY · PI RAMAMURTHY, VISVANATHAN · 2020 to 2024
$1.9M
NEI NIH HHS R01 EY017035NEI NIH HHS R01 EY028035NEI NIH HHS R01 EY031346NIGMS NIH HHS P20 GM144230NIGMS NIH HHS R35 GM148416
6 · The paper itself

Abstract

Mutations in

Indexed as

ADP-Ribosylation FactorsCiliaMorphogenesisRetinal Cone Photoreceptor CellsRetinal Photoreceptor Cell Outer SegmentVision, OcularAnimalsElectroretinographyFemaleGene Knock-In TechniquesMaleMiceMice, Inbred C57BLMice, TransgenicMutationRetinaADP-Ribosylation FactorsArl13b protein, mouseaxonemeblindnessciliacone photoreceptorJoubert syndromephotoreceptor

Identifiers

PMID40721319
PMCPMC12369925

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.