Evidence map›Paper›PMID 40720902›Full record

ArticleJournal of neurosurgery. Case lessons2025

Rescue globus pallidus deep brain stimulation following refractory dystonia treated with subthalamic nucleus deep brain stimulation: illustrative case.

Yamenah Ambreen, Cameron Brandon, Zachary Jordan, Brian Dalm

Abstract read
In one paragraph

Article in Journal of neurosurgery. Case lessons, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yamenah AmbreenThe Ohio State University College of Medicine, Columbus, Ohio.ORCID 0009-0007-5450-3841
Cameron BrandonDepartment of Neurosurgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Zachary JordanDepartment of Neurology, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Brian DalmDepartment of Neurosurgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.ORCID 0000-0001-5044-0686

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDystonia is a group of movement disorders that can result in tremor, abnormal posturing, and difficulty with coordinated movements. Medically intractable dystonia can be treated with deep brain stimulation (DBS). Dystonia refractory to DBS can be rescued with DBS to another region. Here, the authors report one of the first cases of dystonia initially treated with subthalamic nucleus (STN) DBS rescued by globus pallidus (GPi) DBS. OBSERVATIONS: A 42-year-old male presented with progressive and disabling left hemidystonia along with toe curling, foot inversion, and arm posturing. Previous therapies include botulinum toxin, phenol injections, and bilateral STN-DBS. STN-DBS initially provided relief with symptoms, but its effect faded over time. Multiple attempts were made to optimize lead placement, but they were ultimately unsuccessful. Bilateral GPi-DBS was performed through several programming sessions. A brain laboratory lead localization and brain sense survey were performed to determine the ideal settings. The patient demonstrated significant improvements with his more severe symptoms and is now regaining a better quality of life. LESSONS: There have been several cases of refractory dystonia following GPi-DBS being rescued by STN-DBS. However, there have been no cases describing GPi-DBS rescuing dystonia refractory to STN-DBS. This case provides insight into a novel method of treating dystonia refractory to STN-DBS. https://thejns.org/doi/10.3171/CASE24886.

Indexed as

deep brain stimulationdystoniaglobus pallidus internusneuromodulationsubthalamic nucleus

Identifiers

PMID40720902
PMCPMC12305359

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.